Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (2): 131-135.doi: 10.6040/j.issn.1673-3770.0.2020.206

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Research progress of exosomes in thyroid cancers

ZHANG Yiyi1Overview,XUE Gang2, JIN Chunting3Guidance   

  1. 1. Basic Medical College, Hebei North University, Zhangjiakou 075000, Hebei, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075061, Hebei, China;
    3. Department of Pathology, Hebei North University, Zhangjiakou 075000, Hebei, China
  • Published:2021-04-20

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Abstract: The exosome are extracellular vesicle with a diameter of 50-140 nm, generated by almost all types of cell and carrying nucleic acids, proteins, lipids, and metabolites. They are found in all biological fluids such as blood,milk,urine etc.and play a key role in intercellular communication by delivering active biomolecules. This paper rviews the general situation, functions and applications of exosomes, summarize the effects of exosomal miRNAs and circRNAs in thyroid carcinoma and the potential as a new type of biomarkers.

Key words: Thyroid cancers, Exosome, Extracellular vesicles, MicroRNAs(miRNA), Biomarkers

CLC Number: 

  • R736.1
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