中耳间变性大T细胞淋巴瘤1例并文献复习

doi:10.6040/j.issn.1673-3770.0.2021.318

Abstract

Abstract: Objective To investigate the clinical characteristics, diagnosis and treatment methods of middle ear anaplastic large T-cell lymphoma, to enable its early diagnosis. Methods A patient with middle ear anaplastic large T-cell lymphoma was retrospectively reviewed,along with previous cases of middle ear lymphoma found in the literature. Results Lymphoma mostly occurs in the bones, bone marrow, subcutaneous tissue and spleen, but rarely in the middle ear. There is no superficial lymphadenopathy at the onset of middle ear lymphoma, which usually presents as earache, hearing loss, and ear discharge(serous, purulent, or bloody). Disease progression, peripheral facial nerve paralysis and extra cranial-intracranial complications may occur. The lesion appeared as a high and uneven soft tissue density on the CT and the bone destruction was irregular and worm-eaten. The lesion area was wide and the enhanced scan showed obvious enhancement. Diagnosis requires pathological biopsy and immunohistochemistry. Chemotherapy is the main treatment. Conclusion Middle ear anaplastic large T-cell lymphoma is extremely rare and its clinical and imaging findings are non-specific. Therefore it is imperative to carefully consider the patient’s medical history, systemic examination findings, pathological biopsy findings and immunohistochemistry to diagnose middle ear anaplastic large T-cell lymphoma at an early stage.

Key words: Middle ear, Tumor, Anaplastic large T cell lymphoma, Immunocombination chemistry, Otology surgery

CLC Number:

R764.92

ZHAO Xiaobing,ZHANG Dawei, CHEN Renjie. A case of middle-ear anaplastic large T- cell lymphoma and literature review[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 7-14.

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A case of middle-ear anaplastic large T- cell lymphoma and literature review

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