Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (4): 105-110.doi: 10.6040/j.issn.1673-3770.0.2022.530

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Misdiagnosis of primary nasopharyngeal tuberculosis: a case report and literature review

LI Guangjin1,2,3, WANG Yan2,3, LIU Feifei2,3, SONG Xicheng2,3, SUN Yan2,3   

  1. 1. School of Clinical Medicine, Weifang Medical University, Weifang 261000, Shandong, China2. Department of Otorhinolaryngology Head and Neck Surgery, Yuhuangding Hospital of Qingdao University, Yantai 264000, Shandong, China;
    3. Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai 264000, Shandong, China
  • Published:2023-07-27

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Abstract: Objective This study aimed to provide a clinical reference for otolaryngologists by identifying the clinical characteristics of nasopharyngeal tuberculosis and causes of misdiagnosis. Methods This retrospective analysis included data of one case of misdiagnosis of primary nasopharyngeal tuberculosis(PNT). We analyzed the clinical characteristics of the case and reasons why it was easily misdiagnosed, considering the relevant literature. Results The clinical manifestations of PNT were related to the degree of hyperplasia of the nasopharyngeal lesions, which usually do not have clinical tuberculosis-related manifestations and cannot easily be distinguished from chronic nasopharyngitis. In cases wherein tuberculosis diagnosis is not clear enough based on pathological examination, tuberculosis-related tests should be performed and patients should be instructed to adhere to close follow-up. Regarding treatment, systemic anti-tuberculosis agents are still the mainstay of therapy. Conclusion PNT is relatively rare and lacks typical clinical manifestations, making it be easily misdiagnosed. Histopathology combined with tuberculosis-related tests could help improve diagnosis of PNT. Furthermore, regularly close follow-up is also an important key factor in avoiding misdiagnosis.

Key words: Primary nasopharyngeal tuberculosis, Chronic nasopharyngitis, Misdiagnosis

CLC Number: 

  • R766.04
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