石墨烯养护鼻罩结合尘螨的皮下特异性免疫治疗在尘螨变应性鼻炎患者中的应用分析

doi:10.6040/j.issn.1673-3770.0.2023.360

Abstract

Abstract: Objective To analyze the effect of graphene-cured nasal mask combined with subcutaneous specific immunotherapy of dust mite in patients with dust mite allergic rhinitis. Methods A total of 102 patients with dust mite allergic rhinitis were selected and divided into two groups according to the random number table method, namely the control group(51 cases)and the observation group(51 cases), the control group was treated with subcutaneous specific immunotherapy(dust mite allergen vaccine immunization)with dust mites alone, and the subcutaneous specific immunotherapy + graphene cured nasal mask treatment of dust mites in the observation group was compared to compare the clinical effects, adverse reactions, clinical symptom scores, immune function indexes, Inflammatory factor indexes, quality of life scores. Results The total effective rate of the observation group was higher than that of the control group(Z=5.005, P=0.025). Compared with the control group, the difference in clinical symptom scores, immune function indicators, inflammatory factors, and quality of life scores was higher in the observation group before and after treatment(all P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups(χ2=0.614, P=0.433). Conclusion Compared with dust mite allergen vaccine alone, graphene-cured nasal mask combined with dust mite allergen vaccine can alleviate the clinical symptoms and improve the treatment effect of dust mite allergic rhinitis patients.

Key words: Graphene curing nose mask, Dust mite allergen vaccine, Dust mite allergic rhinitis, Inflammatory factors, Immune function

CLC Number:

R765

ZHANG Lijing, FENG Xiaoxing, LIU Nanxian, ZHAO Huiming, CHEN Yuehua. Graphene cured nasal mask combined with subcutaneous specific immunotherapy of dust mite in patients with dust mite allergic rhinitis application analysis[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 26-32.

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Graphene cured nasal mask combined with subcutaneous specific immunotherapy of dust mite in patients with dust mite allergic rhinitis application analysis

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