Abstract:

Objective   To explore the therapeutic efficacy of fluticasone propionate nasal spray in the perioperative endoscopic sinus surgery. Methods   Chronic rhinosinusitis and  nasal polyps patients were randomized into the control group(96 cases) and the treatment group(94 cases).  The control group was routinely treated by antibiotic and mucus discharged drugs (gelomyrtol forte). Besides routine treatment, topical corticosteroids application in nasal cavity (fluticasone propionate nasal spray) was added in the treatment group. Results  The results of operative bleeding duration, post-operative sinus clean duration, post-operative sinus epithelialize duration and therapeutic efficacy were in favor of the treatment group when compared with the control group (P<0.05). Conclusion  Topical corticosteroids application in nasal cavity (fluticasone propionate nasal spray) can improve and consolidate the therapeutic efficacy of endoscopic sinus surgery.

Key words: Corticosteriod; Local application; Rhinosinusitis, chronic; Treatment outcome