Abstract:

Objective   To investigate the clinical efficacy of compound trabeculectomy combined with sodium hyaluranate on secondary glaucoma following anterior uveitis. Methods  During the process of compound trabeculectomy, sodium hyaluranate was injected into the anterior chamber and under the sutured scleral flaps in 37 cases (37 eyes) of the experimental group. The other 29 cases (29 eyes) in control group were injected with B.S.S. solution. Visual acuity，intraocular pressure，thickness and angle of anterior chamber and the type of blebs in the two groups were recorded and statistically analyzed. Postoperative follow-up ranged from 9 to 15 months. Results   A significant difference in the success rate was found between the two groups(P<0.05). The incidences of functional filtration blebs and filtration patency were significantly higher in the experimental group than in the control group(P<0.05). The incidence of flat anterior chamber was significantly lower in the experimental group than in the control group(P<0.05). No significant difference was found in the visual acuity improvement between the two groups (P>0.05). Conclusion   A small amount of sodium hyaluranate injected into anterior chamber and under sutured scleral flap can restrain filtration adherence and raise surgery quality of compound trabeculectomy on secondary glaucoma following anterior uveitis.

Key words:  Anterior uveitis; Secondary glaucoma; Sodium hyaluranate; Trabeculectomy