Abstract:

Objective   To investigate the clinical and pathologic characteristics of follicular dendritic cell sarcoma (FDCS) of tonsil to improve the diagnosis and treatment. Methods   The histopathological, immunohistochemical, clinical characteristics and treatment of a tonsil FDCS case was reviewed. One year after the extended tonsillectomy, the FDCS recurred and were further treated with radical neck dissection and postoperative radiotherapy. Related literature were reviewed. Results   The patient were followed up for 5 years without recurrence and lost function. Conclusions   The FDCS of tonsil is rare and often misdiagnosed  The diagnosis is based on the histopathology and immunohistochemistry. Recurrence were reported after the surgery. We recommend the primary treatment of FDCS of tonsil is surgery. Postoperative radiotherapy can be performed depending on the tumor extension and size.

Key words: Tonsil; Sarcoma; Follicular dendritic cell sarcoma; Immunohistochemistry; Ultrastructure