JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (3): 29-30.doi: 10.6040/j.issn.1673-3770.0.2014.416

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Efficacy of fluconazole for fungal otitis externa (71 cases report)

HUANG Xiongchao, LIAO Shouben, DONG Shiting, ZHONG Haijian, QIN Yongqian   

  1. Department of Otolaryngology, Zhongshan People's Hospital, Zhongshan 542699, Guangxi, China
  • Received:2014-12-25 Revised:2015-04-07 Published:2015-06-16

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Abstract: Objective To investigate the method and efficacy of fluconazole in the treatment of fungal otitis externa. Methods 139 patients diagnosed as fungal otitis externa were divided into 2 groups, with 71 patients in observation group treated with fluconazole bathing, and 68 patients in control group treated with miconazole nitrate cream. All patients were followed up for 1 year. Results Both methods were effective in the treatment of fungal otitis externa, but the recurrence rate of the control group was higher than the observation group one year later(P<0.05). Conclusion The recurrence rate of fluconazole bathing to treat fungal otitis externa is low. This method is simple and easy to apply, with good compliance.

Key words: Fluconazole, Mycosis, Otitis externa

CLC Number: 

  • R764.11
[1] 吴洪巧, 管善国, 王文娟.45例外耳道真菌病诊治体会[J].山东医大基础医学院学报, 2001, 15(3):151-152. WU Hongqiao, GUAN Shanguo, WANG Wenjuan. The experience of 45 fungal disease diagnosis and treatment of external auditory canal[J]. J Preclin Med Coll Shandong Med Univ, 2001, 15(3):151-152.
[2] 蒙慧菊, 李和忠, 莫秀林.150例外耳道炎分泌物细菌培养结果及原因分析[J].右江民族医学院学报, 2009, 31(1):75.MENG Huiju, LI Hezhong, MO Xiulin. 150 cases of ear infections, bacterial culture of secretion analysis result and reason[J]. J Youjiang Med Coll Nation, 2009, 31(1):75.
[3] 陈浩.耳内镜下清理并涂布联苯苄唑乳膏治疗真菌性外耳道炎[J].湖北科技学院学报:医学版, 2013, 27(3):197-199.CHEN Hao. Under ear endoscope cleaning and coating. Bifonazole Cream treatment of fungal externa[J]. J Hubei Univer Sci Technol: Med Sci, 2013, 27(3):197-199.
[4] 张群, 罗四维, 戴润芝, 等.氟康唑注射液外用治疗耳部真菌病疗效观察[J].临床耳鼻咽喉头颈外科杂志, 2007, 21(1):37-38. ZHANG Qun, LUO Siwei, DAI Runzhi, et al. Observation Fluconazole Injection otomycosis external treatment efficacy[J]. Clin J Otorhinolarynol Head Neck Surg, 2007, 21(1):37-38.
[5] 黄奖章, 莫及来, 关文锦, 等.达克宁霜治疗真菌性外耳道炎206例的临床观察[J].右江医学, 2010, 38(6):752. HUANG Jiangzhang, MO Jilai, GUAN Wenjin, et al. Clinical observation of miconazole nitrate cream in the treatment of fungal otitis externa in 206 cases[J]. Youjiang Med J, 2010, 38(6):752.
[6] 袁艳.复方酮康唑软膏治疗真菌性外耳道炎疗效观察[J].上海医药, 2012, 33(3):39, 42. YUAN Yan. Observation Compound Ketotonazole Cream treatment of fungal otitis externa effect[J]. Shanghai Med Pharmaceu J, 2012, 33(3):39, 42.
[7] 李正贤, 江文, 刘阳云, 等.派瑞松联合耳内镜清理冲洗治疗真菌性外耳道炎的临床研究[J].临床军医杂志, 2013, 41(2):176-179. LI Zhengxian, JIANG Wen, LIU Yangyun, et al. Clinical study on Pevisone combined with canal clean-up and irrigation using ear endoscopy in the treatment of fungal otitis externa[J]. Clin J Med Offi, 2013, 41(2):176-179.
[8] 敬光怀.真菌性外耳道炎88例临床疗效对比观察[J].当代医学, 2010, 16(9):3. JING Guanghuai. Clinical curative effects of 88 cases with fungal otitis externa[J]. Contemp Med, 2010, 16(9):3.
[9] 张远芬, 李谨, 张群, 等.制霉素片治疗外耳道真菌病[J].中国耳鼻咽喉头颈外科, 2007, 14(9):530. ZHANG Yuanfen, LI Jin, ZHANG Qun, et al. Nystatin Tablets in otomycosis[J]. Chin Otolaryngol Otolaryngol Head Neck Surg, 2007, 14(9):530.
[10] 刘春青, 刘海成, 侯峥.耳内镜下治疗真菌性外耳道炎77例[J], 山东大学耳鼻喉眼学报, 2013, 23(4):51-52. LIU Chunqing, LIU Haicheng, HOU Zheng. Management of 77 fungal otitis externa by otoendoscope[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 23(4):51-52.
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