铁必复颗粒治疗缺铁感音神经性聋患者的疗效分析

doi:10.6040/j.issn.1673-3770.0.2016.190

Abstract

Abstract: Objective To explore the clinical efficacy of Tiebifu Granule in the treatment of deafness with iron deficiency. Methods A total of 217 cases with iron deficiency including 163 cases of unilateral deaf and 54 cases of bilateral deaf were screened from 1 214 cases of sensorineural deafness and randomly divided into 2 groups: Tiebifu Granule group(n=109, taking Tiebifu Granule for 2 months)and control group(n=108, taking vitamin B1, mesylate, or methycobal for 2 months). The average threshold and serum ferritin were observed 1-3 days before medication, and 1 month and 2 months after taking medicine. Results One month after taking medicine, the serum ferritin level returned normal in 71.6% and 10.2% cases in the Tiebifu Granule group and control group, while the rate increased to 89% and 13.9% two months after taking medicine, showing significant difference between the two groups(P<0.001). The total effective rate of Tiebifu Granule group and control group was 52.3% and 22.2%, respectively, with significant difference between the two groups(P<0.001). Relevance between hearing improvement and serum ferritin increase was found in the Tiebifu Granule Group, but not in the control group. Conclusion Tiebifu Granule can effectively treat sensorineural deafness with iron deficiency.

Key words: Sensorineural deafness, Hearing threshold, Tiebifu Granule, Serum ferritin

CLC Number:

R764

References

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Clinical efficacy of Tiebifu Granule in the treatment of deafness with iron deficiency.

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