Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (5): 39-45.doi: 10.6040/j.issn.1673-3770.1.2020.064

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Location and frequency characteristics of vestibular dysfunction in patients with nonsyndromic auditory neuropathy

  

  • Received:2020-07-03 Published:2020-11-17

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Abstract: Objectives This study was aimed at determining vestibular involvement and the location and frequency of vestibular dysfunction in patients with auditory neuropathy. Methods Twenty patients with non-syndromic auditory neuropathy were enrolled. Using vestibular test battery, we calculated the ocular vestibular-evoked myogenic potential(oVEMP), cervical vestibular-evoked myogenic potential(cVEMP), video head impulse test(vHIT), suppression head impulse paradigm(SHIMP), and caloric test results. Results The oVEMP and cVEMP were calculated for all patients, and the abnormality rates were 85% and 95%, respectively, showing no significant difference. The vHIT in the lateral, anterior, and posterior semicircular canals, and SHIMP in the lateral canals were calculated for 11 patients(22 ears), and the abnormality rates were 14%, 18%, 9%, and 9%, respectively, showing no significant difference among the four tests. Nineteen patients exhibited a 74% abnormality rate for the caloric test. Of the 11 patients with the SHIMP and vHIT results, 82% showed abnormal caloric test results, which was much higher than the abnormality rate of SHIMP and vHIT. Conclusion Patients with auditory neuropathy showed vestibular involvement, and the superior and inferior vestibular components, including the vestibular peripheral receptors and nerves, had an equal probability of dysfunction. All the otolith organs and semicircular canals could be involved. The possibility of dysfunction was equal for different portions of the semicircular canal, while the functional involvement was more likely to be observed in low-frequency tests.

Key words: Nonsyndromic, Auditory neuropathy, Vestibular function, Location, Frequency

CLC Number: 

  • R764
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