Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (5): 85-92.doi: 10.6040/j.issn.1673-3770.0.2021.145

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Comparison of anterior segment analyzers: the Oculyzer and CASIA2

XU Wen, ZHENG Yan, FU Caiyun, ZHANG Li, WANG Yue, ZHANG Qiulu, LIU Jing, HU Yabin, ZHAI Changbin   

  1. Beijing Tongren Ophthalmology Center / Beijing Tongren Ophthalmology Center Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Published:2021-09-29

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Abstract: Objective To compare the differences in corneal refractive power, corneal thickness, and Q value measured by the Oculyzer and CASIA2 devices in patients with myopia. Methods This study evaluated 249 eyes in 125 patients with myopia. The steep keratometry diopter(Ks), flat keratometry diopter(Kf), mean keratometry diopter(Km), astigmatism degree, Q values of the anterior and posterior corneal surfaces, central corneal thickness(CCT), and thinnest point of the corneal thickness(TCT)were recorded. The differences and agreement between measurements were evaluated using paired t-tests and Bland Altman plots., respectively. Results The Ks, Kf, and Km values of the anterior corneal surface measured by the Oculyzer and CASIA2 differed significantly ［(44.23±1.71)D vs(44.38±1.64)D,(42.71±1.39)D vs(42.87±1.35)D, and(43.45±1.48)D vs(43.63±1.44)D, respectively)］(all P<0.001). The astigmatism degrees of the anterior corneal surface(1.51±0.90)D vs(1.50±0.87)D did not differ significantly(P=0.98). The Ks, Kf, and astigmatism degrees of the posterior corneal surface measured by the two instruments also differed significantly ［(-6.50±0.86)D vs(-6.35±0.29)D,(-6.02±0.26)vs(-5.97±0.24)D, and(0.52±0.22)D vs(0.38±0.15)D, respectively］(all P<0.001). The Km values of the posterior corneal surface(-6.17±1.15)D vs(-6.16±0.25)D did not differ significantly(P=0.87). The CCT and TCT measured by the two instruments ［(542.86±33.04)μm vs(529.53±32.35)μm and(539.72±33.39)μm vs(524.66±32.40)μm differed significantly(all P<0.001). The Q values of the anterior corneal surface measured by the two instruments(-0.33±0.12)vs(-0.33±0.13)did not differ significantly(P=0.62). The Q values of the posterior corneal surface(-0.28±0.17)vs(-0.38±0.16)significantly(P<0.001). Bland-Altman analysis showed that the 95% limit of agreement(LoA)of the anterior and posterior corneal surface refractive power, astigmatism degree, and Q values measured by the two devices were relatively narrow and showed good consistency. However, the 95%LoA of CCT and TCT between the two devices was relatively wide and showed poor consistency. Conclusions The differences in corneal refractive power, corneal thicknesses, and Q values between the Oculyzer and CASIA2 suggest the need for comprehensive analysis and selection in clinical practice.

Key words: Oculyzer, CASIA2, Anterior segment analyzer, Corneal refractive power, Corneal thickness

CLC Number: 

  • R765.21
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