Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (2): 58-63.doi: 10.6040/j.issn.1673-3770.0.2021.336

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Effect of microwave ablation on solid thyroid nodules with different initial volumes

LI Siyao1,2, BAO Yuhan3, LI Xinying4, SUN Xiaojing2, CAO Xiaoli2   

  1. 1. Qingdao University School of Medicine, Qingdao 266005, Shandong, China;
    2. Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai 264000, Shandong, China;
    3. Wuxi School of Medicine, Jiangnan University, Wuxi 214122, Jiangsu, China;
    4. School of Medical Imaging, Binzhou Medical University, Yantai 264000, Shandong, China;
  • Published:2022-04-15

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Abstract: Objective This research aimed to investigate the effects of ultrasound-guided microwave ablation(MWA)on benign solid thyroid nodules with different initial volumes. Methods Eighty-two benign solid nodules that had received MWA were divided into four groups according to the initial volume(>12, 9-12, 4-8, and <4 cm3). The ablation parameter and volume reduction rate(VRR)for the four groups were calculated, and the recurrence rate and complication rate were recorded. Results The volume of nodules gradually reduced after 1, 3, 6, and 12 months; the VRR was 37.93±19.48%, 61.69±14.76%, 74.27±12.93%, and 84.92±10.35%, respectively(P<0.05). Compared with those of other groups, for the initial volume ≥ 12 cm3 group, the ablation time was longer and ablation power was higher(P<0.05); the pain score was higher(P<0.05); and the VRR was significantly lower at 3, 6, and 12 months(P<0.05). The recurrence rate was 14.6%(12/82). One case of transient hoarseness was recorded in the largest volume group. Conclusion Microwave ablation is a safe and effective treatment for benign solid thyroid nodules, and the curative effect of relatively small nodules is more significant.

Key words: Microwave ablation, Thyroid nodules, Solid

CLC Number: 

  • R736.1
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