JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (6): 12-15.doi: 10.6040/j.issn.1673-3770.1.2017.038

Previous Articles     Next Articles

Optimal management of differentiated thyroid carcinoma in children.

XU Shuhang1, LI Chunrui2, LIU Chao1   

  1. 1. Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, Jiangsu, China;2. Department of Endocrinology and Metabolism, Sunshine Union Hospital, Weifang 261061, Shandong, China
  • Received:2017-10-09 Online:2017-12-16 Published:2017-12-16

Abstract: Pediatric thyroid masses are rare and their risk of malignancy is high; however, the prognosis of differentiated thyroid carcinoma in children is more favorable. It is important to assess the risk of malignancy based on medical history, physical examination, laboratory tests, imaging tests, and fine needle aspiration cytology. Although the treatment of benign thyroid nodules in children is more conservative, total thyroidectomy is always the first choice for children with thyroid carcinoma. Whole body scans with radioactive iodine should be performed regularly after surgery alongside thyroglobulin determination.

Key words: Differentiated thyroid carcinoma, Child, Thyroid nodules

CLC Number: 

  • R736.1
[1] Hanley P, Lord K, Bauer AJ. Thyroid disorders in children and adolescents: a review[J]. JAMA Pediatr, 2016, 170(10): 1008-1019.
[2] Brown RE, Harave S. Diagnostic imaging of benign and malignant neck masses in children-a pictorial review[J]. Quan Imag Med Surg, 2016, 6(5): 591-604.
[3] Neiva F, Mesquita J, Paco LS, et al. Thyroid carcinoma in children and adolescents: a retrospective review[J]. Endocrinol Nutr, 2012, 59(2):105-108.
[4] Limdunham JE, Erdem TI, Alsabban K, et al. Ultrasound risk stratification for malignancy using the 2015 american thyroid association management guidelines for children with thyroid nodules and differentiated thyroid cancer[J]. Pediatr Radiol, 2017, 47(4): 429-436.
[5] Al Nofal A, Gionfriddo MR, Javed A, et al. Accuracy of thyroid nodule sonography for the detection of thyroid cancer in children: systematic review and meta-analysis[J].Clin Endocrinol, 2016, 84(3): 423-430.
[6] Ba??塂 VN, Aycan Z, Cetinkaya S, et al. Thyroid nodules in children and adolescents: a single institution's experience[J]. J Pediatr Endocrinol Metab, 2012, 25(7-8):633-638.
[7] Shirian S, Daneshbod Y, Haghpanah S, et al. Spectrum of pediatric tumors diagnosed by fine-needle aspiration cytology[J]. Medicine, 2017, 96(6):5480.
[8] 李春睿, 徐书杭, 刘超, 等. 儿童甲状腺结节的诊断与治疗[J].国际内分泌代谢杂志,2013,33(1): 23-25. LI Chunrui, XU Shuhang, LIU Chao, et al. Diagnosis and treatment of thyroid nodules in children[J]. Inter J Endoc Metab, 2013, 33(1): 23-25.
[9] Wiersinga WM. Management of thyroid nodules in children and adolescents[J]. Hormones, 2007, 6(3): 194-199.
[10] 胡欣, 李春睿, 徐书杭, 等. 2015年美国甲状腺学会儿童甲状腺结节与分化型甲状腺癌管理指南的介绍[J]. 中华内分泌代谢杂志,2016, 32(4):265-268. HU Xin, LI Chunrui, XU Shuhang, et al. Introduction to the management guideline for children with thyroid nodules and differentiated thyroid cancer[J]. Chin J Endocrinol Metab, 2016, 32(4):265-268.
[11] Machac J. Thyroid cancer in pediatrics[J]. Endoc Metab Clin North Am, 2016, 45(2): 359-404.
[12] Verburg FA, Santen HMV, Luster M. Pediatric papillary thyroid cancer: current management challenges[J]. Onco Targets Ther, 2016, 10: 165-175.
[13] Parisi MT, Mankoff D. Differentiated pediatric thyroid cancer: correlates with adult disease, controversies in treatment[J]. Sem Nucl Med, 2007, 37(5): 340-356.
[14] Wang C, Chen X, Wei X, et al. Recurrence factors and prevention of complications of pediatric differentiated thyroid cancer[J]. Asian J Surg. 2017, 40(1): 55-60.
[15] Xu L, Liu Q, Liu Y, et al. Parameters influencing curative effect of 131i therapy on pediatric differentiated thyroid carcinoma: a retrospective study[J]. Med Sci Monit, 2016, 22: 3079-3085.
[16] Savvides P, Nagaiah G, Lavertu P, et al. Phase II trial of sorafenib in patients with advanced anaplastic carcinoma of the thyroid[J]. Thyroid, 2013, 23(5): 600-604.
[17] Cohen SM, Mukerji R, Timmermann BN, et al. A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers[J]. Am J Surg, 2012, 204(6): 895-900.
[18] Karnak(·overI), ArdıçlıB, Ekinci S, et al. Papillary thyroid carcinoma does not have standard course in children[J]. Pediatr Surg Int, 2011, 27(9): 931-936.
[19] Tracy ET, Roman SA. Current management of pediatric thyroid disease and differentiated thyroid cancer[J]. Curr Opin Oncol, 2016, 28(1): 37-42.
[20] Filipovic A, Vuckovic L, Mijovic M. Invasive follicular thyroid carcinoma infiltrating trachea[J]. Vojnosanit Pregl, 2011, 68(10): 891-894.
[21] Boelaert K, Horacek J, Holder RL, et al. Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration[J]. J Clin Endoc Metab, 2006, 91(11): 4295-4301.
[22] Waguespack SG, Francis G. Initial management and follow-up of differentiated thyroid cancer in children[J]. J Natl Compr Canc Net, 2010, 8(11): 1289-1300.
[1] LIU Bing, LI Bei, ZHANG Li, CHEN Min, ZHANG Jie. Clinical Analysis of Benign Paroxysmal Vertigo in preschool and school-age children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 58-60.
[2] XU Ming, LUO Xinggu, TANG Hongbo, JIANG Qingshan. Clinical characteristics and prognostic factors for sudden idiopathic sensorineural hearing loss in children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 41-44.
[3] LIU Dawei, ZHANG Yu, LI Chenglin, CHEN Xiumei, SONG Xicheng. Use of enhanced recovery after surgery in children with obstructive sleep apnea syndrome during the perioperative period [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 19-22.
[4] XU Hongming, GU Meizhen, CHEN Fang, JIANG Yugang, LI Xiaoyan. Establishment of a three-dimensional pediatric larynx finite element model [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 82-85.
[5] LIU Dabo. Evaluation of sleep structure disorder in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 6-8.
[6] LI Yanzhong, ZHANG Tai. Problems we face in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 1-5.
[7] XU Zhifei, NI Xin. Post-surgery management in children with obstructive sleep apnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 9-13.
[8] WANG Yan, SHI Xiaoli. The relationship between allergic reaction and children obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 14-18.
[9] YANG Wei, ZHENG Li, XU Zhifei. Long-term follow-up study on non-invasive ventilation in children with moderate to severe [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 19-24.
[10] QIU Shuyao, LIU Dabo, ZHONG Jianwen, YANG Liqiang. Analysis of coblation complications in children with obstructive sleep apnea-hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 34-37.
[11] ZHONG Jianwen, LIU Dabo, LUO Xiangqian, HUANG Zhenyun, QIU Shuyao, CHENG Chao, YANG Liqiang, YI Xinhua, ZENG Jinhong. The application of wearable devices in the diagnosis of children obstructive sleep apnea [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 30-33.
[12] GAO Jinliang, NIAN Wanqing, LI Shuo. Evaluation of the clinical curative effect of nose surgery in combination with nasal corticosteroids in [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 38-42.
[13] SUN Guochen, SUN Yan, ZHANG Hong, WANG Baowei. Clinical characteristics and treatment of differentiated thyroid carcinoma in children. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(6): 25-28.
[14] PAN Yongjie, PANG Wenhui, SUN Guochen, SUN Yan, ZHANG Hong. Expression and clinical significance of Heparanase and D2-40 in pediatric thyroid carcinoma. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(6): 29-32.
[15] JING Shanglin.. Diagnosis and treatment of upper airway cough syndrome in children. [J]. J Otolaryngol Ophthalmol Shandong Univ, 2017, 31(6): 87-91.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!