Abstract: To observe the effect of propofol combined with remifentanil anesthesia for uvulopalalopharyngoplasty (UPPP). Methods: Forty patients with obstructive sleep apnea hypopnea syndrome (OSAHS) were randomly divided into two groups: Remifentanil group(R group,n=20) and Fentany group (F group,n=20). All patients were given general anesthesia with tracheal intubation. In R group, 1.52?μg/kg remifentanil was given for induction, and then 0.30.6?μg/kg Remifentanil per minute for maintenance. In F group, 23?μg/kg Fentanyl was given for induction, and then 810?μg/kg Fentanyl for maintenance. ECG, MAP, HR, SPO2, the time that recovering of spontaneous breath and of extubation were monitored. Results: MAP was significantly decreased in the two groups (P＜0.05), but HR were slowly down (P＜0.05) in R group. MAP and HR in R group were lower than those in F group. The recovering of spontaneous breath and of extubation in R group was earlier than that in F group. Conclusion: Propofol combined with remifentanil anesthesia is better for patients undergoing UPPP.

Key words: Remifentanil, Propofol, Fentanyl, Obstructive sleep apnea hypopnea syndrome, Uvulopalatopharyngoplasly