Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (4): 114-127.doi: 10.6040/j.issn.1673-3770.0.2024.354

• Original Article • Previous Articles     Next Articles

Evaluation of the efficacy and safety of site-specific acupuncture for the treatment of sudden hearing loss: a systematic review and network Meta-analysis

ZHENG Zehao1, WEI Jiali1, LIU Jiatao1, ZHOU Yuqi1, SUN Wenting2, LI Yuxuan2, BAI Peng2   

  1. 1. Department of Acupuncture, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing 100029, China2. Department of Acupuncture, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
  • Online:2025-07-20 Published:2025-08-11

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Abstract: Objective To systematically evaluate and compare the efficacy and safety of site-specific acupuncture in the treatment of sudden hearing loss. Methods Randomized controlled trials on the efficacy and safety of acupuncture for sudden hearing loss were retrieved from PubMed, the Cochrane Library, Web of Science, SinoMed, CNKi, Wanfang, and VIP databases. Literature was screened and checked independently by two investigators using NoteExpress software to determine the inclusion of literature, data were extracted using Excel, risk of bias was assessed using the Cochrane Collaboration's Risk of Bias(RoB)2.0 tool, and Meta-analysis was performed using R software. Results A total of 20 studies involving 1,453 patients were included, evaluating 13 different interventions. The RoB 2.0 assessment revealed that one study had a low risk of bias, while the remaining studies exhibited a moderate risk of bias. The results of the Meta-analysis indicated that acupuncture was effective in sudden hearing loss, with cervical acupuncture combined with auricular acupuncture showing the greatest efficacy. Additionally, the combination of acupuncture and western medicine demonstrated superior effectiveness. In the ranking of the surface under the cumulative ranking curve(SUCRA)value for the primary outcome(the number of patients with hearing enhancement of more than 15 dB after treatment), cervical acupuncture + auricular acupuncture + western medicine(92.3)ranked highest, followed by cephalic and facial acupuncture(80.84), cervical acupuncture + western medicine(70.64), and so on. The ranking of the secondary outcome pure tone hearing threshold was highest for cephalic and facial acupuncture(88.42), followed by cephalic and facial acupuncture + auricular acupuncture + western medicine(74.15). Regarding safety, five studies reported relevant outcomes, with one study observing a case of subcutaneous hematoma and bruising in both groups, though this did not impact the progress of the trial. Conclusion Site-specific acupuncture is effective in treating sudden hearing loss, especially cervical acupuncture combined with auricular acupuncture, and shows a favorable safety profile. However given the limited number of included studies, further high-quality randomized controlled trials are needed to validate these findings.

Key words: Acupuncture Location Specificity, Sudden Hearing Loss, Systematic Review, Efficacy Ranking, Network Meta-Analysis

CLC Number: 

  • R245
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