Abstract: To evaluate the longterm effect of laser subepithelial keratomileusis(LASEK) for superhigh myopia(≥-10.00?D). MethodsEightythree cases (151 eyes)of superhigh myopia who had been treated with LASEK in our hospital from December 2003 to January 2006 were followed up from 25 to 49 months (mean 35.34±6.45 months). Before the operations, visual acuity, the best corrected visual acuity, and diopter was 0.010.1(mean 0.053±0.025), 0.51.2(mean 0.098±0.145), and -10.00～-14.50D(mean -11.01±1.19D), respectively. ResultsAfter the operations, visual acuity was 0.21.5 (mean 1.01±0.26), and was 1.0 or better in 120 eyes (79.47%), and 0.6 or better in 142 eyes (94.04%). In addition, 5 eyes had a 0.5level Haze and 1 eye had a 1level Haze. ConclusionLASEK is an effective and good method to correct superhigh myopia and is stable and safe with satisfactory visual acuity and less complication.