Table of Content

24 October 2006 Volume 20 Issue 5

  

Articles

Pathogens of chronic suppurative otitis media and their clinical significances

ZHU Xiao-pin,LOU Zheng-cai

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  397-398 . 

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To analyze the pathogens of chronic suppurative otitis media and to test their antibiotic susceptibility. Methods: Pus from inner external auditory canal or middle ear was collected from 108 patients with chronic suppurative otitis media and cultured for pathogen identification and antibiotic susceptibility test. Results: Nine kinds of microbes were isolated, and their strain number were as follows: pseudomonas aeruginosa, 29(26.85%); staphylococcus aureus, 25(23.15%); proteus, 22(20.37%); others, 28(25.92%); and combined pathogens, 3(2.78%). All isolated pseudomonas aeruginosa were imipenem and polymyxinsensitive. Conclusion: Pathogen identification and susceptibility test are essential for appropriate antibiotic therapy in chronic suppurative otitis media.

Clinical observation of hyperbaric oxygen and ginaton in the treatment of sudden deafness

QIAO Xiao-feng,ZHANG Hao-jie

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  406-407 . 

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To explore the effect of hyperbaric oxygen and ginaton in the treatment of sudden deafness. Methods: Fifty patients with sudden deafness were divided into hyperbaric oxygen group and control group at random; hearing threshold, blood gas analysis and ocular fundus were measured and compared. Results: The overall response rate, hearing threshold, and arterial partial oxygen pressure in hyperbaric oxygen group was significantly higher than in control group; the ocular fundus was not significantly different in the two groups. Conclusion: It is effective for the combination of hyperbaric oxygen and ginaton to treat sudden deafness.

〖KH+9.2mmD]FGF2 expression in olfactory epithelium of patients with dysosmia caused by chronic sinusitis

LIU Qing-hua,LI Zhi-chun,LI Rui-yu,LIN Chang

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  410-412 . 

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To study the pathogenesis of dysosphresia in patients with chronic sinusitis, and to discuss the expression and significance of FGF2 in olfactory epithelium. Methods: There were 32 cases of chronic sinusitis in the experimental group, and 11 cases in the control group. FGF2 was examined by the method of immunohistochemistry. Results: The expression of FGF2 in the olfactory epithelium of 32 patients suffering from dysosmia was higher than in the control group(P＜0.05). Conclusion: FGF2 promotes regeneration in the olfactory epithelium, which is decreased notably at chronic sinusitis and may lead to dysosmia.

Endoscopic management for pharyngeal bursitis

CHENG Ze-xing,LEI Da-peng,ZHANG Pan

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  431-432 . 

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To study the method and effect of endoscopic surgery for pharyngeal bursitis. Methods： Twentyseven cases of pharyngeal bursitis were treated under endoscopy. Among them, 11 cases were treated by powered tissueremoval system, and 16 were treated by temperaturecontrolled radiofrequency. Result： Twenty cases were cured and seven cases were improved. Conclusion： Endoscopic surgery for pharyngeal bursitis has advantages of clear view, minimal invasion, safety and effect. Temperaturecontrolled radiofrequency is better than powered tissueremoval system.

Expression of ABAD/HADH Ⅱ in laryngeal squamous cell carcinoma and vocal polyp

ZHANG Hui-ping,ZHANG Peng-fei,SHANGGUAN Han-jing,LAN shu-zhan

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  444-446 . 

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To determine the expression of ABAD/HADH Ⅱ in human laryngeal carcinoma and to investigate whether their expressions relate to proliferation of laryngeal carcinoma cells. Method: Expression of ABAD /HADH Ⅱ was detected in patients with laryngeal squamous cell carcinoma or vocal polyp by immunohistochemical method. Results： ABAD /HADH Ⅱ mainly expressed in the cytoplasm of laryngeal squamous cell cancinoma cells, especially of the proliferating cells. The immunohistochemistry result indicated that the expression of ABAD /HADH Ⅱ was significantly higher in the squamous cell cancinoma than in the vocal polyp (P<0.05). Conclusion: The expression of ABAD/HADH Ⅱ in the laryngeal squamous cell cancinomatissues is significantly higher than in the normal tissues, suggesting that ABAD /HADH Ⅱ may play a role in the proliferation of laryngeal squamous cell cancinoma.

Puncture and intubation through cricothyriod membrane for acute laryngeal obstruction

LIU Hong,PANG Ling,XIN Pei-yao,WANG Kun,SHI Xiu-na,HU Xiao-xia,SUN Guang-yan

JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2006, 20(5):  447-448 . 

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To explore the effect of puncture and intubation through cricothyriod membrane on acute laryngeal obstruction. Methods: From July 1998 to March 2005, 286 patients with acute laryngeal obstruction had received the puncture and intubation through cricothroid membrane, and their clinical data were retrospectively studied. Results: All operations were successful, and the surgical time of puncture was less than one minute and the bleeding amount was less than 3?ml. No complication was found after operation. Conclusion: This surgical procedure is safe, effective and easy for acute laryngeal obstruction.