山东大学耳鼻喉眼学报

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OSAHS与心血管疾病研究进展

赵源庆1,郭家亮1综述张峰2审校   

  1. 1.天津市泰达医院耳鼻咽喉科; 2.天津市泰达国际心血管病医院心内科, 天津  300457
  • 收稿日期:2013-07-11 出版日期:2014-04-16 发布日期:2014-04-16
  • 通讯作者: 郭家亮,主任医师。 E-mail:tdent@126.com
  • 作者简介:赵源庆。 E-mail:zhaoyq101@sohu.com

Research progress of obstructive sleep apnea hypopnea syndrome and cardiovascular diseases

ZHAO Yuan-qing1, GUO Jia-liang1, ZHANG Feng2   

  1. 1. Department of Otolaryngology-Head and Neck Surgery, Tianjin Teda Hospital, Tianjin 300457, China; 2. Department of Cardiology, Tianjin Teda International Cardiovascular Hospital, Tianjin 300457, China
  • Received:2013-07-11 Online:2014-04-16 Published:2014-04-16

摘要: 阻塞性睡眠呼吸暂停低通气综合征(OSAHS)由于睡眠时气道塌陷而引起反复缺氧、白天嗜睡等症状,且与高血压、心律失常、冠心病和心力衰竭等心血管疾病关系密切。由于二者之间存在较多共同危险因素,OSAHS在促进心血管疾病发生、发展过程中的病理生理机制还有待深入研究。目前,OSAHS与心血管疾病的病理生理联系和治疗后对心血管疾病的改善作用,使得两者之间的相关性成为研究热点。

关键词: 危险因素, 心血管疾病, 睡眠呼吸暂停, 阻塞性

Abstract: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition caused by intermittent airway collapse during sleep resulting in repetitive hypoxia and excessive daytime sleepiness. The epidemiologic evidence has confirmed that OSAHS can drastically promote the risks of cardiovascular diseases, including hypertension, cardiac arrhythmias,coronary arterial disease,and congestive heart failure. However, the mechanisms behind the increased cardiovascular diseases risks in OSAHS remain elusive. The potential pathophysiological interaction of cardiovascular diseases with OSAHS, and improvement of cardiovascular diseases after OSAHS treatment make the studies on the correlation between OSAHS and cardiovascular diseases to be hotspot in recent years.

Key words: Cardiovascular diseases, Risk factors, Sleep apnea hypopnea syndrome, obstructive

中图分类号: 

  • R767.7
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