重症肌无力患者声反射检测的临床意义

山东大学耳鼻喉眼学报

重症肌无力患者声反射检测的临床意义

白艳霞，王萱

（西安交通大学医学院第一附属医院耳鼻咽喉-头颈外科，西安 710061）

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-02-16 发布日期:2009-02-16

Clinical value of the acoustic reflex in patients with myasthenia gravis

BAI Yanxia, WANG Xuan

(Department of Otorhinolaryngology & Head and Neck Surgery, First Affiliated Hospital, Medical College of Xi′an Jiaotong University， Xi′an 710061， China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-02-16 Published:2009-02-16

摘要/Abstract

摘要： 目的探讨声反射检查在重症肌无力患者诊断及病情监测方面的应用价值。方法对以头颈部和五官症状为首发症状而到我科初诊的16例重症肌无力患者进行纯音测听和声导抗检测，并在肌肉注射甲基硫酸新斯的明0.5～1.0?mg，30?min后复查声反射。检测用0.5、1.0、2.0和4.0?kHz的纯音作同侧和对侧刺激，比较用药前后有无声反射及其阈值、振幅变化、有无衰减等。结果13例患者声反射4项指标中至少有1项改善，判为阳性，阳性率高达81.3%。余3例患者声反射4项指标均无改善，为阴性。结论声反射检测具有敏感、使用方便等优点，是一种客观、可靠、无创伤的检查方法，在重症肌无力的诊断及病情监测方面有一定的应用价值。

关键词: 重症肌无力, 声反射, 新斯的明

Abstract: ObjectiveTo study the clinical value of the acoustic reflex in patients with myasthenia gravis. Methods16 patients who were diagnosed as myasthenia gravis with initial head and neck symptoms were determined by a pure tone audiometer and acoustic immitance measurement and then the acoustic reflex was reexamined 30 min after injection of Neostigminum sulfate 0.5～1?mg. Results13 patients (81.3%) had positive results. ConclusionThe acoustic reflex has advantages such as sensitive, convenient and so on, and is an objective, reliable and atraumatic examination in diagnosis and surveillance of myasthenia gravis.

中图分类号:

R764.45

白艳霞，王萱
. 重症肌无力患者声反射检测的临床意义[J]. 山东大学耳鼻喉眼学报, 2009, 23(1): 46-47 .

BAI Yanxia, WANG Xuan
. Clinical value of the acoustic reflex in patients with myasthenia gravis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2009, 23(1): 46-47 .

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