JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (4): 7-10.doi: 10.6040/j.issn.1673-3770.0.2014.386

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Hearing screening and risk factors of hearing impairment in premature infants.

WANG Guoqiang1, ZHAO Chunhong1, HUO Hong1, GONG Zhiyun1, SONG Weiwei1, YAN Lixia2, LI Xuehua2, WANG Weili2   

  1. 1. Department of Otolaryngology, The Second People's Hospital of Luohe City in Henan Province, Luohe 462000, Henan, China;
    2. Hearing Center of Children's Hospital in Luohe City, Luohe 462000, Henan, China
  • Received:2014-12-02 Revised:2015-04-07 Online:2015-08-16 Published:2015-08-16

Abstract: Objective To investigate the risk factors of hearing impairment by analyzing the results of hearing screening in the premature infants in the neonatal intensive care unit. Methods A total of 821 premature infants, admitted to the neonatal intensive care unit form January 2010 to December 2013, were screened for hearing functions. The risk factors for no passing in the screenings were analyzed. Results The failure rates in initial and secondary screening were 61.0% and 16.0%, respectively. The failure rate was 9.4% in the automatic auditory brainstem response (AABR) test conducted at three months after birth. With the growth of gestational age, pass rate increased and degree of hearing disorders decreased in the mean time. Logistic regression analysis showed that very low birth weight, hyperbilirubinemia, infection and suffocation were risk factors for hearing, while, gestational age > 32 weeks was protective factor (OR=0.499, P=0.022). Low birth weight was independent risk factor for hearing screening and hearing impairment (OR=2.385, P=0.038). Conclusion Due to immature development, premature babies suffer from high incidence of hearing loss. The smaller the gestational age is, more commonly hearing damages occur. Low birth weight, hyperbilirubinemia, infections are risk factors for hearing impairment. Early detection and timely follow-up are neccessary.

Key words: Neonatal intensive care center, Premature infant, Risk factor, Hearing screening, Hearing impairment

CLC Number: 

  • R764.4
[1] Erenberg A, Lemons J, Sia C, et al. Newborn and infant hearing loss: detection and intervention. American Academy of Pediatrics. Task Force onNewborn and Infant Hearing, 1998- 1999[J]. Pediatrics, 1999, 103(2):527-530.
[2] Jiang Z D, Zhou Y, Ping L L, et al. Brainstem auditory response findings in late preterm infants in neonatal intensive care unit[J]. Acta Paediatr, 2011, 100(8):51-54.
[3] Halpin K S, Smith K Y, Widen J E, et al. Effects of universal newborn hearing screening on an early intervention program for children with hearing loss, birth to 3 yr of age[J]. J Am Acad Audiol, 2010, 21(3):169-175.
[4] American Academy of Pediatrics, Joint Committee on Infant Hearing. Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs[J]. Pediatrics, 2007, 120(4):898-921.
[5] 陶方英,龚正鹏.TEOAE与AABR在高危新生儿听力筛查中的联合应用[J].中华耳科学杂志,2013,11(2):235-238.
TAO Fangying, GONG Zhengpeng. TEOAE with AABR joint application in high-risk newborn hearing screening[J]. Chin J Otology, 2013, 11(2):235-238.
[6] 黄治物.婴幼儿听力损失的早期诊断评估及干预*(4)[J].听力学及言语疾病杂志,2013,21(5):561-562.
HUANG Zhiwu. Evaluation of early diagnosis of hearing loss in infants and relevant intervention *(4)[J]. J Audiol Speech Pathol, 2013, 21(5):561-562.
[7] 邓忠,罗铭华,董运鹏,等.郴州市121352例新生儿听力筛查结果分析[J].听力学及言语疾病杂志,2014,22(3):306-308.
DENG Zhong, LUO Minghua, DONG Yunpeng, et al. On the Results of Hearing Screening among newborns in the city of chen zhou[J]. J Audiol Speech Pathol, 2014, 22(3):306-308.
[8] 庄帝钱,赵芳,李耀武, 等.不同新生儿危重症评分对极低出生体质量儿永久致残的预测价值[J]. 广东医学,2013,34(15):2314-2317.
ZUANG Diqian, ZHAO Fang, LI Yaowu. et al. Different neonatal critical care scoring very low birth weight infant permanently disabled the predictive value[J]. Guangdong Med, 2013, 34(15):2314-2317.
[9] 宋文萍,晋芙莉.极低出生体质量儿159例临床分析[J]. 中国妇幼健康研究,2013,24(4):563-564,599.
SONG Wenping, JIN Fuli. Clinical analysis of 159 cases of very low birth weight infants[J]. Chin J Woman Child Health, 2013, 24(4):563-564,599.
[10] Neocleous C, Adramerina A, Limnaios S, et al. A comparison between transcutaneous and total serum bilirubin in healthy-term greek neonates with clinical jaundice[J]. Prague Med Rep, 2014, 115(1-2):33-42.
[11] Mesić I, Milas V, Medimurec M, et al. Unconjugated pathological jaundice in newborns[J]. Coll Antropol, 2014, 38(1):173-178.
[12] Xia Y F, Liu C Q, Li H X, et al. Investigation of risk factors for hearing impairment in premature infants[J]. Zhongguo Dang Dai Er Ke Za Zhi, 2013, 15(12):1050-1053.
[13] 王丽.围生期巨细胞病毒感染监测与预后评估[J].国际儿科学杂志,2012,39(3):237-241. WANG Li. Monitoring and prognosis of perinatal Cytomegalovirus infection assessment[J]. J Inter Paediat, 2012, 39(3):237-241.
[14] 梁玲芳.婴儿巨细胞病毒感染致听力受损的研究进展[J]. 国际儿科学杂志,2010,37(5):475-478. LIANG Lingfang. Infant hearing loss caused by Cytomegalovirus infection progress[J]. J Inter Paediat, 2010, 37(5):475-478.
[15] 杨崇玲,叶清,王幼勤,等.窒息新生儿与正常新生儿听力筛查结果分析[J].听力学及言语疾病杂志,2010,18(6):549-552. YANG Chongling, YE Qing, WANG Youqin, et al. Asphyxia with normal newborn hearing screening results analysis[J]. J Audiol Speech Pathol, 2010, 18(6):549-552.
[16] 李永奇,丁大连,蒋海燕,等.速尿引起的小鼠耳蜗血管纹缺血缺氧性病变[J].中国中西医结合耳鼻咽喉科杂志,2010,18(3):123-127. LI Yongqi, DING Dalian, JIANG Haiyan, et al. Furosemide-induced cochlear stria vascularis of hypoxic-ischemic lesion[J]. Chin J Otorhinolaryngol Integ Med, 2010, 18(3):123-127.
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