JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (3): 9-12.doi: 10.6040/j.issn.1673-3770.0.2015.060

Previous Articles     Next Articles

Changes of vestibular function in patients with obstructive sleep apnea-hypopnea syndrome

YIN Xueling   

  1. Department of Otolaryngology, Laiwu Central Hospital of Shandong Energy Xinwen Mining Group, Laiwu 271103, Shandong, China
  • Received:2015-01-29 Revised:2015-04-29 Published:2015-06-16

PDF (PC)

348

Abstract: Objective To observe the changes of vestibular function in patients with obstructive sleep apnea hypopnea syndrom (OSAHS). Methods The video of nystagmus figure (VNG) check of 42 OSAHS cases and 30 healthy controls were examined. The results of spontaneous nystagmus test, oculomotor center test, vestibular bithermal calorid test and positional test conducted in the two groups were compared. Results The results of spontaneous nystagmus test and oculomotor center test were statistically different between the two groups (P<0.05). In OSAHS cases, the apnea hypopnea index (AHI) and history were closely related to vestibular dysfunction (P<0.05). Conclusion OSAHS may cause dysfunction of central vestibule. The changes of vestibular function can be timely detected with VNG tests and can help us further understand OSAHA effects on body systems.

Key words: Vestibular function, Video of nystagmus, Central, Sleep apnea hypopnea, obstructive

CLC Number: 

  • R766.7
[1] 中华医学会呼吸病学分会睡眠呼吸障碍学组.阻塞性睡眠呼吸暂停低通气综合征诊治指南(2011年修订版)[J]. 中华结核和呼吸杂志, 2012, 35(1): 9-12. The Sleep-related Breathing Disorder Group of Respiratory Diseases Branch in Chinese Medical Association. Diagnosis and treatment of obstructive sleep apnea-hypopnea syndrome Guide (The Revised edition in 2011)[J]. Chin J Tuberc Respir Dis, 2012, 35(1): 9-12.
[2] Hernández Montero E, Fraile Rodrigo J J, De Miguel García F, et al. The role of video-nystagmography in the diagnosis of acoustic neuroma[J]. Acta Otorrinolaringol Esp, 2003, 54(6): 413-416.
[3] Amor Dorado J C, Rubio Rodríguez J P, Costa Ribas C, et al. Video-nystagmography findings in healthy elderly subjects[J]. Acta Otorrinolaringol Esp, 2003, 54(3): 215-219.
[4] 李晓东, 张冬梅, 高枫, 等. 眼震电图在椎-基底动脉供血不足性眩晕诊断中的应用[J]. 北京医学, 2002, 24(5): 304-306. LI Xiaodong, ZHANG Dongmei, GAO Feng, et al. The application of electrical diagram of nystagmus in vertebral-basilar artery insufficiency vertigo diagnostic[J]. Beijing Med J, 2002, 24(5): 304-306.
[5] 皮丽宏, 李晓明, 王俊阁, 等. 阻塞性睡眠呼吸暂停低通气综合征患者听性脑干反应及前庭脊髓反射的观察[J]. 听力学及言语疾病杂志, 2006, 14(5): 330-333. PI Lihong, LI Xiaoming, WANG Junge, et al. The observation of auditory brainstem response and vestibular spinal reflex in patients with obstructive sleep apnea hypopnea syndrom[J]. J Audiol Speech Pathol, 2006, 14(5): 330-333.
[6] Gallina S, Dispenza F, Kulamarva G, et al. Obstructive sleep apnoea syndrome (OSAS): effects on the vestibular system[J]. Acta Otorhinolaryngol Ita, 2010, 30(6): 281-284.
[7] Urban P P, Schlegel J, Ellrich J, et al. Electrophysiological brainstem investigations in obstructive sleep apnoea syndrome[J]. J Neurol, 1996, 243(2): 171-174.
[8] Nakayama M, Kabaya K. Obstructive sleep apnea syndrome as a novel cause for Ménière's disease[J]. Curr Opin Otolaryngol Head Neck Surg, 2013, 21(5): 503-508.
[9] Kapsimalis F, Varouehakis G, Manousaki A, et al. Association of sleep apnea severity and obesity with insulin resistance, C-reactive protein, and leptin levels in male patients with obstructive sleep apnea[J]. Lung, 2008, 186(4): 209-217.
[10] Esteve E, Castro A, López-Bermejo A, et al. Serum inter 1eukin-6 correlates with endothelial dysfunction in healthy men independently of insulin sensitivity[J]. Diabetes Care, 2007, 30(4): 939-945.
[11] Scherer E Q, Yang J, Canis M, et al. Tumor necrosis factor-α enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine -1-phosphate signaling[J]. Stroke, 2010, 41(11): 2618-2624.
[12] 佘万东, 张倩, 钱晓云, 等. 重度阻塞性睡眠呼吸暂停低通气综合征耳蜗功能的临床观察[J]. 听力学及言语疾病杂志, 2002, 10(4): 232-235. SHE Wandong, ZHANG Qian, QIAN Xiaoyun, et al. The clinical observation of cochlear function in severe obstructive sleep apnea hypopnea syndrom in patients[J]. J Audiol Speech Pathol, 2002, 10(4): 232-235.
[1] LIU Bing, LI Bei, ZHANG Li, CHEN Min, ZHANG Jie. Clinical Analysis of Benign Paroxysmal Vertigo in preschool and school-age children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 58-60.
[2] LIU Ye, SUN Dianshui, YIN Jinjun, XIA Ming, XU Ying, SUN Jianhua. Vestibular function damage mechanisms in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 14-17.
[3] JIANG Yang1, QIU Jia-ji2, JIN Yu-mei1, LI Ying1. Application of ocular response analyzer in the intraocular pressure measurement [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(4): 58-60.
[4] SONG Qi1, WANG Huan-yi2, QIN Xue-jiao1. Vogt-KoyanagiHarada disease misdiagnosed as central retinitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(2): 7-8.
[5] JIAN Hui-rong, YU Gang, CHEN Gang, LIN Nai-fen, WANG Hai-bo. Correlation between levels of estrogen and auditory and vestibular functions in post-menopause with Meniere′s disease [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(2): 39-41.
[6] XIA Xinchang, CHEN Xuan, LIU Jian, ZHANG Shaoguang, WANG Yu. Association between foveal photoreceptor integrity and visual outcome  in central serous chorioretinophy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(4): 93-96.
[7] WANG Guanghui, YOU Xinying, ZHANG Dan, L Fuli
. Optical coherence tomography combined with fundus photochromy in locating central serous chorioretinopathy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2009, 23(1): 87-89 .
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd