JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (2): 94-97.doi: 10.6040/j.issn.1673-3770.0.2015.372

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Clinical observation on the effects of three surgical methods for pterygium.

WANG Dan, WANG Rui, ZHANG Qiming, WANG Liwen   

  1. Department of Ophthalmology, Affiliated Hospital of Jianghan University(the Sixth Hospital of Wuhan City), Wuhan, 430015, Hubei, China
  • Received:2015-09-02 Online:2016-04-16 Published:2016-04-16

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Abstract: Objective To compare the therapeutic effects of simple pterygium excision, pterygium excision combined with free conjunctival flap transplantation and pterygium excision combined with autologous corneal limbus stem cell transplantation in the treatment of pterygium. Methods Totally 162 patients(186 eyes)were randomly divided into Group A, B and C. Group A were treated with simple pterygium excision, Group B with pterygium excision combined with free conjunctival flap transplantation, and Group C with pterygium excision combined with autologous corneal limbus stem cell transplantation. The recurrence rate, incidence of complications and change of tear function after surgeries were compared among the three groups. Result Group A was significantly lower than Group B and C in the cure rate, was higher than Group B and C in the incidence of complications and recurrence rate, and was longer than Group B and C in repair time(P<0.05). The incidence of complications, recurrence rate were lower and cure rate and repair time were better in Group C than those in Group B(P<0.05). The early postoperative tear films stability of Group B and C were better than that of Group A, with statistically significant difference(P<0.05). Conclusion Compared with single pterygium excision and pterygium excision combined with free conjunctival flap transplantation, pterygium excision combined with autologous corneal limbus stem cell transplantation is an effective method to treat pterygium,which can reduce the rate of complications, the recurrence,and improve tear function for patients with pterygium.

Key words: Pterygium, Conjunctival flap transfusion, Tear film, Autologous corneal limbus stem cell transplantation

CLC Number: 

  • R779.6
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