JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (4): 105-108.doi: 10.6040/j.issn.1673-3770.0.2016.002

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Intravitreal injection of conbercept for macular edema secondary to retinal vein occlusion.

YAN Xiaoteng, FENG Jun, KANG Xinle   

  1. Deparment of ophthalmology, Affiliated Huaian Hospital of Xuzhou Medical College, Huaian 223002, Jiangsu, China
  • Received:2016-01-01 Online:2016-08-16 Published:2016-08-16

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Abstract: Objective To explore the effects of intravitreal injection of conbercept for macular edema(ME)secondary to retinal vein occlusion(RVO). Methods A prospective, continuity and uncontrolled clinical case analysis was used. Thirty cases(30 eyes)with ME secondary to RVO in our hospital from September 2014 to February 2015 were selected, in which 9 cases(9 eyes)were central retinal vein occlusion(CRVO)and 21 cases(21 eyes)were branch retinal vein occlusion(BRVO). All cases were treated with intravitreal injection of conbercept for 3 times and followed up for 6 months. Best corrected visual acuity(BCVA)and central macular thickness(CMT)were observed. Results In patients with BRVO, mean BCVA before treatment and 6 months after treatment were(0.77±0.24)logMAR,(0.27±0.19)logMAR, and CMT were(596.8±139.6)μm,(272.6±29.2)μm, respectively, the difference has statistical significance(t=4.483, P<0.05; t=7.189, P<0.05). In patients with CRVO, mean BCVA before treatment and 6 months after treatment were(0.87±0.55)logMAR,(0.43±0.2)logMAR, and CMT were(647.3±163.6)μm,(393.1±121.5)μm, respectively, the difference has statistical significance(t=2.288, P<0.05; t=7.189, P<0.05). Conclusion Intravitreal injections of conbercept is effective for ME secondary to RVO.

Key words: Intravitreal injection, Retinal vein occlusion, Macular edema, Conbercept

CLC Number: 

  • R774.5
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