JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (6): 63-66.doi: 10.6040/j.issn.1673-3770.0.2016.094

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Report of 11 cases of Kimuras disease and review of literature.

JIN Chengxun, ZHAO Xue, LIU Yue, WEI Ning, JIN Chunshun   

  1. Department of Otolaryngology &Head and Neck Surgery, Second Hospital of Jilin University, Changchun 130000, Jilin, China
  • Received:2016-03-08 Online:2016-12-16 Published:2016-12-16

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Abstract: Objective To explorethe clinical signs,symptoms,pathological and laboratory examinations, diagnosis, differential diagnosis and treatmentof Kimuras disease. Methods Clinical data of 11 cases of Kimuras disease were retrospectively reviewed. The characteristics of laboratory and pathological examinations were summarized. The efficacies of surgical treatment and expectant treatmentwere compared. Results All patients were male, aged 39 years on theaverage.The location of the disease was preauricular, retroauricular, neck andsubmaxillay. Theclinical manifestations were painless progressive swelling. Pathologic characteristics were massivelymphadenosis, with the formation of lymphoid folliculars, and eosinophil infiltration. Laboratory examinationsshowed increased peripheral blood eosinophilia, and elevated serum IgE. Conclusion The diagnosis of Kimuras disease is mainly based on clinical manifestations, laboratory and pathological examinations. As the disease is rare, with no specific clinical manifestations, chronic onset, and duration long, misdiagnosis is likely to occur. Kimura disease through or Hormone therapy, radiotherapyand surgery can be adopted to treat this disease.

Key words: Serum IgE, Eosinophils, Kimuras disease

CLC Number: 

  • R780.2
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