J Otolaryngol Ophthalmol Shandong Univ ›› 2018, Vol. 32 ›› Issue (5): 37-40.doi: 10.6040/j.issn.1673-3770.0.2017.205

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Characteristics of tinnitus and the related influencing factors in patients with Menieres disease

HOU Xiaobing1, REN Tongli2, ZHANG Yibo2   

  1. Department of Otology, Fudan University Eye &ENT Hospital, Shanghai 200031, China
  • Received:2017-05-11 Online:2018-09-20 Published:2018-09-20

Abstract: Objective To discuss and analyze the characteristics of tinnitus and the related influencing factors in patients with Menieres disease. Methods A total of 69 patients with Menieres disease were enrolled in our hospital from August 2012 to August 2016, and the pure hearing threshold, tinnitus ipsilateral, course of disease, and sleep quality of the patients were determined. The tinnitus handicap inventory(THI)scale and the dizziness handicap inventory(DHI)scale were used. Results (1) Thirty-one cases showed a low frequency of tinnitus, 15 cases showed a median frequency of tinnitus, and 23 cases showed a high frequency of tinnitus. Tinnitus loudness <10 dB(SL), 10~14 dB(SL), and ≥15 dB(SL)was noted in 41, 18, and 10 cases, respectively; 60 cases showed persistent tinnitus while 9 showed non-persistent tinnitus. Forty-eight patients had no sleep disorders and 21 had sleep disorders. (2) Patients with persistent tinnitus(t=3.099, P=0.008), poor sleep quality(F=2.987, P=0.012), and high tinnitus loudness(F=3.356, P=0.013)had higher THI scores than those with intermittent tinnitus, better sleep quality, and low tinnitus loudness. The THI scores of patients with unilateral tinnitus were lower than those of patients with bilateral tinnitus. (3) Seizure frequency, duration, and average thresholds were positively correlated with the DHI score in multiple linear regression analysis. Conclusion The primary characteristic of tinnitus accompanied by Meniere's disease is low-frequency tinnitus. The severity of tinnitus shows some relationship with tinnitus loudness, duration, and sleep quality. Sex, age, ear, and bimodal test results have no effect on the DHI score, but the onset frequency, duration, and average hearing threshold are the main factors affecting the score. The higher the frequency of the patients, the more severe the dizziness will be.

Key words: Meni disease, Dizziness, Related factors, Tinnitus

CLC Number: 

  • R764
[1] 王庆林, 郭向东, 梅祥胜, 等. 鼓室注射庆大霉素与地塞米松治疗难治性梅尼埃病的疗效分析[J]. 临床耳鼻咽喉头颈外科杂志,2017,31(2):96-99.
[2] 杨凤, 宋任东, 刘伟, 等. 外后半规管阻塞伴内淋巴囊减压治疗顽固性梅尼埃病外科技术探讨[J]. 临床耳鼻咽喉头颈外科杂志,2017,31(2):127-129.
[3] 张祎, 李云, 刘博,等. 梅尼埃病的耳鸣特征与影响因素分析[J]. 中华耳科学杂志,2016,14(2):153-157. ZHANG Yi, LI Yun, LIU Bo, et al. Characteristics and contributing factors of tinnitus in patients with Menieres disease[J]. Chin J Otol, 2016, 14(2):153-157.
[4] 陈晓鸿, 吴子明, 张素珍, 等. 梅尼埃病患者耳鸣疗效分析[J]. 中国听力语言康复科学杂志,2012,10(4):259-262. CHEN Xiaohong, WU Ziming, ZHANG Suzhen, et al. The treatment outcome of tinnitus in patients with Ménières diseas[J]. Chin Sci J Hearing Speech Rehab, 2012, 10(4):259-262.
[5] Roberts DS, Otto S, Chen B, et al. Tinnitus suppression after auditory brainstem implantation in patients with Neurofibromatosis Type-2[J]. Otol Neurotol, 2017, 38(1):118-122.
[6] Kreuzer PM, Poeppl TB, Bulla J, et al. A proof-of-concept study on the combination of repetitive transcranial magnetic stimulation and relaxation techniques in chronic tinnitus[J]. J Neural Transm(Vienna), 2016, 123(10):1147-1157.
[7] Reid SA, Callister R, Katekar MG, et al. Utility of a brief assessment tool developed from the Dizziness Handicap Inventory to screen for Cervicogenic dizziness: a case control study[J]. Musculoskelet Sci Pract, 2017, 30(1):42-48.
[8] 菅慧蓉, 于刚, 陈刚, 等. 梅尼埃病患者眩晕程度的影响因素分析[J]. 现代仪器与医疗,2017,23(1):60-62. JIAN Huirong, YU Gang, CHEN Gang, et al. Analysis of the factors affecting the degree of vertigo in patients with Menieres disease[J]. Modern Inst Med Treat, 2017, 23(1):60-62.
[9] 邹静. 钆增强 MRI 检测内淋巴积水的研究进展[J]. 听力学及言语疾病杂志,2017,25(1):75-85.
[10] 丁玉静, 刘俊秀, 马芙蓉. 内淋巴积水动物模型研究进展[J]. 中华耳科学杂志,2017,15(1):99-104. DING Yujing, LIU Junxiu, MA Furong. Research progress in animal models of endolymphatic hydrops[J]. Chin J Otol, 2017, 15(1):99-104.
[11] Havia M, Kentala E, Pyykko I. Hearing loss and tinnitus in Me-nieres disease[J]. Auris Nasus Larynx, 2002, 29(2):115-119.
[12] Romero Sánchez I, PérezGarrigues H, Rodríguez Rivera V. Clinicalcharacteristics of tinnitus in Ménières disease[J]. Acta Otorhinolaryngol Esp, 2010, 61(5):327-331.
[13] Stephens D, Pyykkö I, Yoshida T, et al. The consequences of tinnitusin long-standing Menieres disease[J]. Auris Nasus Larynx, 2012, 39(5):469-474.
[14] Pan T, Zhao Y, Ding YJ, et al. The pilot study of type Ⅰ allergic reaction in Menieres disease patients[J]. Chin J Otorhinolaryngol Head Neck Surg, 2017, 52(2): 89-92.
[15] 严进, 成红政, 刘爱国. 梅尼埃病患者前庭内淋巴积水程度与其症状和听觉及前庭功能的相关性分析[J]. 听力学及言语疾病杂志, 2015(3):220-225. YAN Jin, CHENG Hongzheng, LIU Aiguo. The correlation analysis of endolymphatic hydrops degree in vestibule and the symptoms and audiovestibular functions in patients with Menieres disease[J]. J Audiol Speech Pathol, 2015(3):220-225.
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