Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (6): 27-30.doi: 10.6040/j.issn.1673-3770.0.2019.588

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Nasal chondromesenchymal hamartoma in infants: A report of two cases and literature review

CHEN Kun,LI Lei, MENG Guozhen, YANG Jun, HOU Dongming   

  1. Department of Otolaryngology & Head and Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
  • Published:2021-01-11

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Abstract: Objective This study aimed to investigate the clinical and pathological features, diagnosis, treatment, and prognosis of nasal chondromesenchymal hamartoma(NCMH)in infants. Method We performed a retrospective analysis of the clinical and pathological data of two infants with NCMH admitted to the Xinhua Hospital affiliated with the Shanghai Jiao Tong University School of Medicine between May 2016 and March 2019. The diagnosis, treatment, and prognosis of the patients were also investigated. Results The NCMHs originated from the nasal cavity or skull base and were completely resected by nasal endoscopy. There was no recurrence in long-term follow-up. Histologically, the mesenchymal cells and collagen fibers showed benign hyperplasia around cartilage structures. Conclusion The clinical manifestations of infant NCMHs are diverse and non-specific; thus, early diagnosis is difficult. Nasal endoscopic surgery is the main treatment method for NCMH and has good clinical effects.

Key words: nasal chondromesenchymal hamartoma, nasal mass, pediatric benign tumors, endoscopic excision, skull base benign tumor

CLC Number: 

  • R765
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[1] HOU Dong-ming, CAO Rong-ping, MENG Guo-zhen, CHENG Lan. Diagnosis and endoscopic treatment of congenital nasal mass of infants [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(3): 36-38.
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