Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (1): 140-144.doi: 10.6040/j.issn.1673-3770.0.2021.450

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Application of optical coherence tomography angiography in macular telangiectasia type 2

LI Pengwei, SU Guangming, LIU Jiangchuan, MU Yalin   

  1. Department of Ophthalmology, Yellow River Sanmenxia Hospital/Huanghe Hospital Affiliated to Henan University of Science and Technology, Sanmenxia 472000, Henan, China
  • Published:2023-02-06

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Abstract: Macular telangiectasia type 2(MacTel 2)is a bilateral, slowly-progressive neurodegenerative disease of the retina mainly characterized by vascular changes. Optical coherence tomography angiography(OCTA)is the ideal tool for detecting MacTel 2. In the early stage of MacTel 2, the telangiectasia shown by OCTA first appeared in the deep capillary plexus on the temporal side of the parafovea, which was closely related to the loss of the ellipsoid zone. Subsequently, the vascular density in the parafovea decreased, primarily involving the capillaries adjacent to the venules. The development of right-angle venules can promote the formation of retinal-choroidal anastomoses. The telangiectasia of some patients with advanced MacTel 2 can progress to neovascularization, and the use of vascular endothelial growth factor inhibitors has a significant effect on untreated neovascularization. This paper reviews the application of OCTA in MacTel 2.

Key words: Macular telangiectasia type 2, Optical coherence tomography angiography, Deep capillary plexus, Right-angle venules, Subretinal neovascularization

CLC Number: 

  • R774.6
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