Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (2): 137-143.doi: 10.6040/j.issn.1673-3770.0.2023.111

• Review • Previous Articles     Next Articles

Clinical and anatomical features of upside-down reversal of vision

YE Qiang1, LUO Song Bazong2, WANG Hao1, LIU Xiaoyan1, MA Jinghai3, NAN Suting1, WANG Jing1, YANG Yi1, LYU Peng1, WANG Degui4, ZHANG Wenfang1   

  1. 1. Department of Ophthalmology, the Second Hospital of Lanzhou University, Lanzhou 730000, Gansu, China2. Nima County Zhongcang Township Health Center, Naqu 853200, Xizang, China 3. Department of Ophthalmology, Lanzhou Bright Ophthalmology, Lanzhou 730000, Gansu, China4. Institute of Human Anatomy and Histoembryology, Basic Medical College, Lanzhou University, Lanzhou 730000, Gansu, China
  • Online:2024-03-20 Published:2024-03-29

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Abstract: Upside-down reversal of vision(UDRV)is a rare clinica symptom of visual distortion or visual illusion that can distort the size, shape, or tilt of an object. Its characteristic is that the patient's visual image undergoes an instantaneous 180° inversion in the coronal position. So far, UDRV has not been reported in China, but in foreign literature, it seriously affects patients' vision and life, bringing unprecedented psychological impact to patients. Here, we discuss the potential etiology and clinical features of UDRV to further improve the understanding of this condition by clinicians, scientifically diagnose and treat the condition, and reduce the psychological distress of patients. Although existing studies on UDRV help us understand the mechanisms of vision formation and possible regulatory mechanisms of vision, the specific etiology and mechanisms are not yet clear. Therefore we propose a hypothesis of visual regulation: "visual-independent regulation center" to explain it.

Key words: Vision, Reversal, Central nervous system injury, Vestibular system dysfunction

CLC Number: 

  • R774.7
[1] Zeller M, Stamps W. Interdisciplinary approach to the treatment of rare visual illusions in a veteran[J]. BMJ Case Rep, 2021, 14(1): 238362. doi:10.1136/bcr-2020-238362
[2] Yap JA. Upside-down vision: a systematic review of the literature[J]. BMJ Neurol Open, 2022, 4(2): 000337. doi:10.1136/bmjno-2022-000337
[3] Deniz O, Keklikoglu HD, Vural G, et al. Acute “upside-down” visual inversion in a patient with multiple sclerosis[J]. Neurol Sci, 2012, 33(3): 635-637. doi:10.1007/s10072-011-0781-3
[4] Bishopp T. Case of optical illusion from hysteria[J]. Med Phys J, 1805, 14(78): 117-118
[5] Pensato U, D'Angelo R, Rinaldi R, et al. Room tilt illusion and persistent hiccups as presenting symptoms of a left PICA stroke: a case report[J].Neurol Sci, 2020, 41(2): 469-471. doi:10.1007/s10072-019-04041-9
[6] River Y, Ben Hur T, Steiner I. Reversal of vision Metamorphopsia[J]. Arch Neurol, 1998, 55(10): 1362. doi:10.1001/archneur.55.10.1362
[7] Seigel AM. Inverted vision in MS[J]. Neurology, 1988, 38(8): 1335. doi:10.1212/wnl.38.8.1335-a
[8] Dog gulu ÇF, Kansu T. Upside-down reversal of vision in multiple sclerosis[J]. J Neurol, 1997, 244(7): 461. doi:10.1007/s004150050123
[9] Okuyucu EE, Okuyucu S, Karazincir S, et al. Acute ‘upside-down’ visual inversion due to multiple sclerosis[J]. Mult Scler, 2008, 14(2): 266-267. doi:10.1177/1352458507082045
[10] Sierra-Hidalgo F, de Pablo-Fernández E, Martín AHS, et al. Clinical and imaging features of the room tilt illusion[J]. J Neurol, 2012, 259(12): 2555-2564. doi:10.1007/s00415-012-6536-0
[11] Arntzen K, Alstadhaug KB. Room tilt illusion and subclavian steal - a case report[J]. BMC Neurol, 2020, 20(1): 369. doi:10.1186/s12883-020-01947-2
[12] Steiner I, Shahin R, Melamed E. Acute “upside down” reversal of vision in transient vertebrobasilar ischemia[J]. Neurology, 1987, 37(10): 1685. doi:10.1212/wnl.37.10.1685-a
[13] 黄岚, 高伟. 内耳疾病继发BPPV的发病机制和临床特征的研究进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 108-113. doi: 10.6040/j.issn.1673-3770.0.2021.445 HUANG Lan, GAO Wei. Research progress on the pathogenesis and clinical characteristics of BPPV secondary to inner ear diseases[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 108-113. doi: 10.6040/j.issn.1673-3770.0.2021.445
[14] 邹曙光, 彭安全, 杨涛, 等. 视觉依赖在前庭疾病中的研究进展[J]. 中华耳科学杂志, 2022, 20(4): 679-683. doi: 10.3969/j.issn.1672-2922.2022.04.027 ZOU Shuguang, PENG Anquan, YANG Tao, et al. Research progress on visual dependence in vestibular diseases[J]. Chinese Journal of Otology, 2022, 20(4):679-683. doi: 10.3969/j.issn.1672-2922.2022.04.027
[15] Graves JS, Krysko KM, Hua LH, et al. Ageing and multiple sclerosis[J]. Lancet Neurol, 2023, 22(1): 66-77. doi:10.1016/S1474-4422(22)00184-3
[16] 侯少瑾, 王云凤, 曹丽丽, 等. 视神经脊髓炎谱系疾病53例与多发性硬化11例的脑脊液检测比较[J]. 山东大学学报(医学版), 2023, 61(1):32-37. doi: 10.6040/j.issn.1671-7554.0.2022.1074 HOU Shaojin, WANG Yunfeng, CAO Lili, et al. Comparison of cerebrospinal fluid detection in 53 patients with neuromyelitis optica spectrum disorder and 11 patients with multiple sclerosis[J]. Journal of Shandong University(Health Science), 2023, 61(1): 32-37. doi: 10.6040/j.issn.1671-7554.0.2022.1074
[17] Ropper AH. Illusion of tilting of the visual environment. Report of five cases[J]. J Clin Neuroophthalmol, 1983, 3(2): 147-151
[18] Charles N, Froment C, Rode G, et al. Vertigo and upside down vision due to an infarct in the territory of the medial branch of the posterior inferior cerebellar artery caused by dissection of a vertebral artery[J]. J Neurol Neurosurg Psychiatry, 1992, 55(3): 188-189. doi:10.1136/jnnp.55.3.188
[19] Stracciari A, Guarino M, Ciucci G, et al. Acute upside down reversal of vision in vertebrobasilar ischaemia[J]. J Neurol Neurosurg Psychiatry, 1993, 56(4): 423. doi:10.1136/jnnp.56.4.423
[20] Solms M, Kaplan-Solms K, Saling M, et al. Inverted vision after frontal lobe disease[J]. Cortex, 1988, 24(4): 499-509. doi:10.1016/S0010-9452(88)80044-3
[21] Kaae C, Cadigan K, Lai K, et al. Vestibulo-ocular dysfunction in mTBI: utility of the VOMS for evaluation and management-A review[J]. NeuroRehabilitation, 2022, 50(3): 279-296. doi:10.3233/nre-228012
[22] Aleman M. Vestibular Disease[J]. Vet Clin North Am Equine Pract, 2022, 38(2):397-407. doi:10.1016/j.cveq.2022.05.008
[23] Akdal G, Toydemir HE, Tanrıverdizade T, et al. Room tilt illusion: a symptom of both peripheral and central vestibular disorders[J]. Acta Neurol Belg, 2017, 117(1): 363-365. doi:10.1007/s13760-016-0628-z
[24] Anzellotti F, Onofrj V, Maruotti V, et al. Autoscopic phenomena: case report and review of literature[J]. Behav Brain Funct, 2011, 7(1): 2. doi:10.1186/1744-9081-7-2
[25] Murakami T, Ohki K. Thalamocortical circuits for the formation of hierarchical pathways in the mammalian visual cortex[J]. Front Neural Circuits, 2023, 17: 1155195. doi:10.3389/fncir.2023.1155195
[26] 鲍敏, 黄昌兵, 王莉, 等. 视觉信息加工及其脑机制[J]. 科技导报, 2017, 35(19): 15-20. doi:10.3981/j.issn.1000-7857.2017.19.001
[27] 李世金, 唐昂藏, 杨必, 等. 虚拟现实视觉训练对集合不足长期疗效的观察[J]. 山东大学耳鼻喉眼学报, 2022, 36(5): 35-40. doi:10.6040/j.issn.1673-3770.0.2021.198 LI Shijin, TANG Angcang, YANG Bi, et al. Long-term effectiveness of virtual reality-based vision therapy for convergence insufficiency: a random clini-cal trial[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(5): 35-40. doi:10.6040/j.issn.1673-3770.0.2021.198
[28] Hellige JB. Hemispheric asymmetry for visual information processing[J]. Acta Neurobiol Exp, 1996, 56(1): 485-497
[29] Slotnick SD, Moo LR, Tesoro MA, et al. Hemispheric asymmetry in categorical versus coordinate visuospatial processing revealed by temporary cortical deactivation[J]. J Cogn Neurosci, 2001, 13(8): 1088-1096. doi: 10.1162/089892901753294383
[30] Fernández E, Alfaro A, Soto-Sánchez C, et al. Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex[J]. J Clin Invest, 2021, 131(23): 151331. doi:10.1172/JCI151331
[31] Kirsch V, Keeser D, Becker-Bense S, et al. Vestibular and visual cortex activity during room tilt illusion[J]. J Neurol, 2017, 264(1): 70-73. doi:10.1007/s00415-017-8457-4
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