Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (6): 8-16.doi: 10.6040/j.issn.1673-3770.0.2024.434

• Lateral Skull Base Surgery Cross-Disciplinary Integration • Previous Articles    

Subtotal resection of facial nerve schwannoma with preservation of facial nerve function

GAO Juanjuan, XU Jia, CHEN Wenjing, LIANG Sichao, GUO Zhenping, CHEN Junyan, GUO Xiang, YI haijin   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, Beijing Tsinghua Changgung Hospital/ School of Clinical Medicine, Tsinghua University, Beijing 102218, China
  • Published:2025-11-19

Abstract: Objective The present study aims to investigate the indications of subtotal resection of facial nerve schwannoma with facial nerve-preserving surgery for patients with mild facial nerve paralysis(HB Ⅰ-Ⅱ)and obvious accompanied symptoms. Methods A retrospective analysis of the clinical data of three cases of facial nerve schwannoma that underwent subtotal resection with facial nerve-preserving surgery was conducted. The analysis encompassed the clinical manifestations, auxiliary examinations, operative approaches, and postoperative prognoses. Results Of the three patients, one exhibited facial nerve function of HB Ⅱ prior to surgery, while the other two demonstrated normal facial nerve function preoperatively. Preoperative imaging findings demonstrated that the mass had grown along the course of the facial nerve. Among the patients, one individual exhibited no symptoms of facial palsy prior to surgery, yet EMG results indicated facial nerve impairment. Subtotal resection of the facial nerve schwannoma was performed under intraoperative facial nerve electrophysiological monitoring. Post-operative observations revealed that the function of the facial nerve had been well preserved. Furthermore, no significant changes to facial nerve function were observed in the immediate post-surgical period. Furthermore, no substantial alterations in facial nerve function were detected during the extended follow-up period of up to three years. Conclusion For patients with facial nerve schwannoma, if the patient's facial nerve function is graded HB Ⅱ or better at the time of surgery, and the patient has strong desire to preserve facial nerve function, then subtotal resection of the facial nerve schwannoma can be contemplated, with this being performed under electrophysiological monitoring during surgery.

Key words: Facial nerve schwannoma, Subtotal resection, Facial nerve function, Intraoperative electrophysiological monitoring, Facial nerve electromyography

CLC Number: 

  • R764.9
[1] Dandinarasaiah M, Grinblat G, Keshavamurthy VB, et al. Characteristics and management of facial nerve schwannomas and hemangiomas[J]. Otol Neurotol, 2024, 45(1): 83-91. doi:10.1097/MAO.0000000000004033
[2] Cho YS, Choi JE, Lim JH, et al. Management of facial nerve schwannoma: when is the timing for surgery[J]. Eur Arch Otorhinolaryngol, 2022, 279(3): 1243-1249. doi:10.1007/s00405-021-06765-x
[3] Kitama T, Hosoya M, Oishi N. Facial nerve schwannoma and other benign neoplastic facial nerve lesions[J]. Curr Opin Otolaryngol Head Neck Surg, 2023, 31(5): 300-305. doi:10.1097/MOO.0000000000000913
[4] Loos E, Verhaert N, Darrouzet V, et al. Intratemporal facial nerve schwannomas: multicenter experience of 80 cases[J]. Eur Arch Otorhinolaryngol, 2020, 277(8): 2209-2217. doi:10.1007/s00405-020-05960-6
[5] Lahlou G, Nguyen Y, Russo FY, et al. Intratemporal facial nerve schwannoma: clinical presentation and management[J]. Eur Arch Otorhinolaryngol, 2016, 273(11): 3497-3504. doi:10.1007/s00405-015-3850-z
[6] Dayawansa S, Dumot C, Mantziaris G, et al. Facial nerve schwannoma treatment with stereotactic radiosurgery(SRS)versus resection followed by SRS: outcomes and a management protocol[J]. J Neurol Surg B Skull Base, 2022, 85(1): 75-80. doi:10.1055/a-1990-2861
[7] House JW, Brackmann DE. Facial nerve grading system[J]. Otolaryngol Head Neck Surg, 1985, 93(2): 146-147. doi: 10.1177/019459988509300202
[8] Sim L, Yeoh XY, Tan TE, et al. Intracapsular enucleation of intraparotid facial nerve schwannoma with intratemporal extension[J]. Medeni Med J, 2022, 37(1): 113-118. doi:10.4274/MMJ.galenos.2022.46844
[9] 张全安. 颞骨内微型面神经鞘瘤病理研究[J]. 中华耳鼻咽喉科杂志, 1998(6): 341. doi:10.3760/j.issn:1673-0860.1998.06.007
[10] Perez R, Chen JM, Nedzelski JM. Intratemporal facial nerve schwannoma: a management dilemma[J]. Otol Neurotol, 2005, 26(1): 121-126. doi:10.1097/00129492-200501000-00022
[11] 韩宇, 刘红生, 杨润琴, 等. 面神经鞘膜瘤临床表现及影像学特征分析[J]. 临床耳鼻咽喉头颈外科杂志, 2024, 38(5): 380-385. doi:10.13201/j.issn.2096-7993.2024.05.006 HAN Yu, LIU Hongsheng, YANG Runqin, et al. Analysis of clinical manifestations and imaging features of facial nerve schwannomas[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2024, 38(5): 380-385. doi:10.13201/j.issn.2096-7993.2024.05.006
[12] 迟放鲁, 王正敏, 陈泽宇, 等. 面神经瘤的诊断与处理[J]. 中华耳鼻咽喉头颈外科杂志, 2006, 41(4): 262-265. doi:10.3760/j.issn: 1673-0860.2006.04.007 CHI Fanglu, WANG Zhengmin, CHEN Zeyu, et al. Diagnosis and management of facial nerve neuromas[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2006, 41(4): 262-265. doi:10.3760/j.issn: 1673-0860.2006.04.007
[13] 于海玲, 徐志鹏, 许安廷. 正常人颞骨内鼓乳段面神经的MR成像方法研究[J]. 山东大学学报(医学版), 2008, 46(3): 324-326
[14] Luzha J, Kopp M, Wiesmüller M, et al. Diagnostic challenges and imaging considerations for intraparotid facial nerve schwannoma: a case report and literature review[J]. Am J Case Rep, 2024, 25: e942870. doi:10.12659/AJCR.942870
[15] Yang WL, Zhao JP, Han YY, et al. Long-term outcomes of facial nerve schwannomas with favorable facial nerve function: tumor growth rate is correlated with initial tumor size[J]. Am J Otolaryngol, 2015, 36(2): 163-165. doi:10.1016/j.amjoto.2014.10.019
[16] Li Y, Liu H, Cheng Y. Subtotal resection of facial nerve schwannoma is not safe in the long Run[J]. Acta Otolaryngol, 2014, 134(4): 433-436. doi:10.3109/00016489.2013.871746
[17] 中华耳鼻咽喉头颈外科杂志编辑委员会耳科组,中华医学会耳鼻咽喉头颈外科学分会耳科学组. 术中面神经监测专家共识[J]. 中华耳鼻咽喉头颈外科杂志, 2024, 59(2): 97-106. doi:10.3760/cma.j.cn115330-20231225-00325.
[18] Hasegawa T, Kato T, Kida Y, et al. Gamma Knife surgery for patients with facial nerve schwannomas: a multiinstitutional retrospective study in Japan[J]. J Neurosurg, 2016, 124(2): 403-410. doi:10.3171/2015.3.JNS142677
[19] Jacob JT, Driscoll CL, Link MJ. Facial nerve schwannomas of the cerebellopontine angle: the mayo clinic experience[J]. J Neurol Surg B Skull Base, 2012, 73(4): 230-235. doi:10.1055/s-0032-1312718
[20] Jacob JT, Driscoll CLW, Link MJ. Facial nerve schwannomas of the cerebellopontine angle: the mayo clinic experience[J]. J Neurol Surg B Skull Base, 2012, 73(4): 230-235. doi:10.1055/s-0032-1312718
[21] Hosmann A, Kamdar V, Misra BK. Malignant transformation of vestibular schwannoma following radiosurgery-a case report and review of the literature[J]. Acta Neurochir(Wien), 2024, 166(1): 52. doi:10.1007/s00701-024-05921-6
[22] Yi XL, Chen LY, Liu JP. Malignant transformation of a schwannoma at lumbar intervertebral foramen area in a patient with nonneurofibromatosis[J]. Asian J Surg, 2023, 46(4): 1654-1655. doi:10.1016/j.asjsur.2022.09.11
[1] SUO Anqi, SUN Juxing, NIU Hongyan, ZHOU Yanqiu, NIU Penghao, MAO Wenwei, LI Xiaoyu, YANG Xinxin. Treatment of complex steel-sharps-based ear puncture wound: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 79-83.
[2] Dengyuan WANG, Zhibin CHEN, Guangqian XING. Minimally invasive otoendoscopic surgery: a new path for ear surgery [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 27-30.
[3] MENG Lixin, LI Jian, WEI Shanwen. Insertion of microtubules in tympanic membrane for the treatment of middle ear atelectasis [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 61-65.
[4] YI Xing, WU Xuewen, MEI Lingyun, HE Chufeng, JIANG Lu, CAI Xinzhang, TIAN Xiange, FENG Yong. Experiences of surgical treatment of complicated congenital preauricular fistula. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 64-67.
[5] WANG Dengyuan, CHEN Zhibin, CHEN Ruoxi, ZHAO Xiaonian, CHENG Lei. Clinical efficacy of repairing auricular skin defects with posterior auricular flaps and their preparation with Gauze blotting. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 68-70.
[6] DU Lijun, TONG Jun, CHEN Wenwen, DENG Yaxin, CAI Xunhua, SHAN Liang. Surgical experience of otitis media in patients with one hearing ear only. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 8-10.
[7] ZHU Lin, ZHANG Dejun, GUAN Guofang, GUO Yingyuan. Treatment of huge cholesteatoma in the petrous apex by microscope combined with otoendoscope: report of 1 case. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 101-103.
[8] WANG Xiaoyan, ZHENG Yanqing, ZHENG Hao, YE Qing. Bone ablation in middle ear with pulsed CO2 laser and Er:YAG laser: an experimental study. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 75-79.
[9] LI Dongfang. Application of pedicle temporal muscle flap in the treatment of secondary radical mastectomy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(6): 13-16.
[10] WANG Jian, GE Qian-jin, KANG Li-ping. Advance flap in repairing marginal perforation of tympanic membrane in 27 cases [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(2): 15-16.
[11] MA Zhe, XI Gu-ping, ZHANG She-jiang, CAI AI-jun, HAO Yan-fang, LIANG Bao-lian. Clinical application of canal Wall reconstruction with homograft cortical bone plate in canal wall down tympanoplasty [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(1): 60-62.
[12] BO Lin, SU Fa-ren, DING Jing-hua. Clinical application of negative pressure drainage in ear reconstruction [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(6): 43-.
[13] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(4): 43-.
[14] CHEN Li-yan1, BAO Jing-chuan2, WANG Qiang3, SUN Yan3, SONG Xi-cheng3. Analysis of intracapsular scratch method in treating  96 patients with pseudocyst of the auricle [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(2): 32-.
[15] ZHANG Kai-chang. Therapeutic effect of intact bone external auditory canal myringoplasty on patients with cholesteatoma tymapanitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2011, 25(2): 34-36.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!