Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 59-62.doi: 10.6040/j.issn.1673-3770.1.2018.042

• Academic Discussion • Previous Articles     Next Articles

Paying attention to the 'lateral airway' allergic diseases in children

Qintai YANG*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong, China
  • Received:2018-11-19 Online:2019-01-20 Published:2019-01-28
  • Contact: Qintai YANG E-mail:yang.qt@163.com
  • Supported by:
    国家自然科学基金(81870704);国家自然科学基金(81670912);广州市产学研重大(对外合作)项目(201704030046)

RichHTML

160

PDF (PC)

274

Abstract:

Allergic diseases are autoimmune diseases that involve multi-organ systems producing a variety of clinical manifestations; concurrently, there is an intrinsic and inseparable link between multiple systems and clinical manifestations, producing a variety of manifestations among different age-groups and populations. Focusing on allergic diseases that are associated with the respiratory airway in children is relatively complicated due to the dynamic changes observed with respect to their body structures and immune systems. Allergic rhinitis, allergic asthma, and otitis media with effusion are three examples of allergic respiratory diseases in children that affect the same airway at different anatomical regions, and the correlation between them is receiving greater attention. Whether the upper, lower, and lateral airways could ever truly be in concurrence with each other is worth an in-depth discussion, and thus, we put forward some minor thoughts and suggestions based on the available clinical research and literature.

Key words: Children, Allergic disease, Otitis media with effusion, Lateral airway

CLC Number: 

  • R765.21

Fig.1

The relationship among adenoidal hypertrophy (AH), allergic rhinitis (AR) and otitis media with effusion (OME)"

Fig.2

The left one provides an illustration of "Integration of upper and lower airways". If we add our "lateral airway" into the regular pattern, we'll end up with the following updated diagram calling "Integration of upper, lower and lateral airways""

1 Grossman J . One airway, one disease[J]. Chest, 1997, 111 (2 Suppl): S11- S16.
2 Bousquet J , Van Cauwenberge P , Khaltaev N , et al. Allergic rhinitis and its impact on asthma[J]. J Allergy Clin Immunol, 2001, 108 (5 Suppl): S147- S334.
3 Bousquet J , Khaltaev N , Cruz AA , et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)[J]. Allergy, 2008, 63 (Suppl 86): 8- 160.
doi: 10.1111/j.1398-9995.2007.01620.x
4 韩德民. 过敏性鼻炎[M]. 2版 北京: 人民卫生出版社, 2014.
5 李颖, 赵守琴. 儿童分泌性中耳炎与变应性鼻炎相关研究进展[J]. 中华耳科学杂志, 2016, 14 (2): 295- 298.
doi: 10.3969/j.issn.1672-2922.2016.02.034
LI Ying , ZHAO Shouqin . Advances in clinical research on otitis media with effusion and allergic rhinitis in children[J]. Chinese Journal of Otology, 2016, 14 (2): 295- 298.
doi: 10.3969/j.issn.1672-2922.2016.02.034
6 Zernotti ME , Pawankar R , Ansotegui I , et al. Otitis media with effusion and atopy: is there a causal relationship?[J]. World Allergy Organ J, 2017, 10 (1): 37.
doi: 10.1186/s40413-017-0168-x
7 Tai A , Volkmer R , Burton A . Prevalence of asthma symptoms and atopic disorders in preschool children and the trend over a decade[J]. J Asthma, 2009, 46 (4): 343- 346.
doi: 10.1080/02770900802660998
8 Mandel EM , Casselbrant ML , Rockette HE , et al. Systemic steroid for chronic otitis media with effusion in children[J]. Pediatrics, 2002, 110 (6): 1071- 1080.
doi: 10.1542/peds.110.6.1071
9 Kwon C , Lee HY , Kim MG , et al. Allergic diseases in children with otitis media with effusion[J]. Int J Pediatr Otorhinolaryngol, 2013, 77 (2): 158- 161.
doi: 10.1016/j.ijporl.2012.09.039
10 Tomonaga K , Kurono Y , Mogi G . The role of nasal allergy in otitis media with effusion. A clinical study[J]. Acta Otolaryngol Suppl, 1988, 458: 41- 47.
11 Pau BC , Ng DK . Prevalence of otitis media with effusion in children with allergic rhinitis, a cross sectional study[J]. Int J Pediatr Otorhinolaryngol, 2016, 84: 156- 160.
doi: 10.1016/j.ijporl.2016.03.008
12 Chantzi FM , Kafetzis DA , Bairamis T , et al. IgE sensitization, respiratory allergy symptoms, and heritability independently increase the risk of otitis media with effusion[J]. Allergy, 2006, 61 (3): 332- 336.
doi: 10.1111/j.1398-9995.2006.00971.x
13 邓慧仪, 杨钦泰, 王玮豪, 等. 儿童腺样体肥大合并变应性鼻炎对分泌性中耳炎发生率的影响[J]. 中山大学学报(医学科学版), 2017, 38 (1): 101- 105.
doi: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2017.0016
DENG Huiyi , YANG Qintai , WANG Weihao , et al. Incidence of otitis media with effusion in adenoid hypertrophy with allergic rhinitis in children[J]. Journal of Sun Yat-Sen University(Medical Sciences), 2017, 38 (1): 101- 105.
doi: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2017.0016
14 Hurst DS . Efficacy of allergy immunotherapy as a treatment for patients with chronic otitis media with effusion[J]. Int J Pediatr Otorhinolaryngol, 2008, 72 (8): 1215- 1223.
doi: 10.1016/j.ijporl.2008.04.013
15 吴佳欐, 陈淑梅, 田欣, 等. 腺样体肥大儿童伴变应性鼻炎与分泌性中耳炎的相关性分析[J]. 山东大学耳鼻喉眼学报, 2013, 27 (6): 53- 56.
WU Jiali , CHEN Shumei , TIAN Xin , et al. Relationship between allergic rhinitis and secretory otitis media in children with adenoid hypertrophy[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2013, 27 (6): 53- 56.
16 Takeuchi K , Fujita Y , Tomemori T , et al. Analysis of T cell receptor beta chain repertoire in middle ear effusions[J]. Ann Otol Rhinol Laryngol, 1996, 105 (3): 213- 217.
doi: 10.1177/000348949610500307
17 Boisvert P , Wasserman SI , Schiff M , et al. Histamine-induced middle ear effusion and mucosal histopathology in the guinea pig[J]. Ann Otol Rhinol Laryngol, 1985, 94 (2 Pt 1): 212- 216.
doi: 10.1177/000348948509400224
18 Nguyen LH , Manoukian JJ , Tewfik TL , et al. Evidence of allergic inflammation in the middle ear and nasopharynx in atopic children with otitis media with effusion[J]. J Otolaryngol, 2004, 33 (6): 345- 351.
doi: 10.2310/7070.2004.03073
19 Nguyen LH , Manoukian JJ , Sobol SE , et al. Similar allergic inflammation in the middle ear and the upper airway: evidence linking otitis media with effusion to the united airways concept[J]. J Allergy Clin Immunol, 2004, 114 (5): 1110- 1115.
doi: 10.1016/j.jaci.2004.07.061
20 Downs BW , Butehorn HFrd , Prazma J , et al. Action of histamine on eustachian tube function[J]. Otolaryngol Head Neck Surg, 2001, 124 (4): 414- 420.
doi: 10.1067/mhn.2001.113943
21 Ebert CS Jr , Rose AS , Blanks DA , et al. Immune modulatory oligonucleotides in prevention of nasal allergen-induced Eustachian tube dysfunction in rats[J]. Otolaryngol Head Neck Surg, 2007, 137 (2): 250- 255.
doi: 10.1016/j.otohns.2007.03.004
22 Cengel S , Akyol MU . The role of topical nasal steroids in the treatment of children with otitis media with effusion and/or adenoid hypertrophy[J]. Int J Pediatr Otorhinolaryngol, 2006, 70 (4): 639- 645.
doi: 10.1016/j.ijporl.2005.08.013
23 崔艳红, 韩富根. 儿童分泌性中耳炎治疗中应用糖皮质激素疗效分析[J]. 中华耳科学杂志, 2013, 11 (3): 448- 450.
doi: 10.3969/j.issn.1672-2922.2013.03.025
CUI Yanhong , HAN Fugen . Nasal steroids for the treatment of secretory otitis media in children[J]. Chinese Journal of Otology, 2013, 11 (3): 448- 450.
doi: 10.3969/j.issn.1672-2922.2013.03.025
24 Rosenfeld RM , Shin JJ , Schwartz SR , et al. Clinical practice guideline: otitis media with effusion (update)[J]. Otolaryngol Head Neck Surg, 2016, 154 (1 Suppl): S1- S41.
doi: 10.1177/0194599815623467
25 Williamson I . Otitis media with effusion[J]. Clin Evid, 2006, (15): 814- 821.
[1] Chuangli HAO,Wenjing GU. Recognizing the etiology of chronic cough in children of different ages [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 20-24.
[2] Chuanhe LIU. The prevalence, diagnosis and management of asthma in children in China [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 28-32.
[3] YANG Yaowei, LU Yingxia, GU Qinglong. Research on visit characteristics of children with acute laryngitis in Beijing between 2013 and 2017 and the correlation of the visit characteristics with meteorological factors and air pollutants [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 88-93.
[4] XU Ming, LUO Xinggu, TANG Hongbo, JIANG Qingshan. Clinical characteristics and prognostic factors for sudden idiopathic sensorineural hearing loss in children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 41-44.
[5] LIU Bing, LI Bei, ZHANG Li, CHEN Min, ZHANG Jie. Clinical Analysis of Benign Paroxysmal Vertigo in preschool and school-age children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 58-60.
[6] LIU Dabo. Evaluation of sleep structure disorder in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 6-8.
[7] LI Yanzhong, ZHANG Tai. Problems we face in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 1-5.
[8] XU Zhifei, NI Xin. Post-surgery management in children with obstructive sleep apnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 9-13.
[9] WANG Yan, SHI Xiaoli. The relationship between allergic reaction and children obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 14-18.
[10] QIU Shuyao, LIU Dabo, ZHONG Jianwen, YANG Liqiang. Analysis of coblation complications in children with obstructive sleep apnea-hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 34-37.
[11] ZHONG Jianwen, LIU Dabo, LUO Xiangqian, HUANG Zhenyun, QIU Shuyao, CHENG Chao, YANG Liqiang, YI Xinhua, ZENG Jinhong. The application of wearable devices in the diagnosis of children obstructive sleep apnea [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 30-33.
[12] GAO Jinliang, NIAN Wanqing, LI Shuo. Evaluation of the clinical curative effect of nose surgery in combination with nasal corticosteroids in [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 38-42.
[13] XIE Rilin, ZHANG Zhiping. Budesonide nasal drops in head extension position improve otitis media with effusion in children with adenoid hypertrophy: a case-study of 31 patients [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(1): 65-67.
[14] MA Zhaoen, ZHAI Jinming, LIAO Libing, YANG Zhen. Short-term effect of eustachian tube balloon dilation in the treatment of chronic otitis media with effusion. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 54-56.
[15] PAN Hongguang, WANG Jumei, CHEN Guowei, WU Zebin. Olfactory function in healthy senior grade students in Shenzhen city. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 71-74.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] WANG Xiao-feng,LIN Chang,CHENG Jin-mei . Expression of ABAD in inner ears and its clinical significance in different age mice[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 207 -211 .
[2] BAI Guang-ping,LI Jun,DONG Pin . Endscopic surgery for chronic nasosinusitis and nasal polyps in 180 cases[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 242 -243 .
[3] YU Zhi-liang,WANG Wei-wei,WANG Ming-hua . Excision of huge epiglottis cysts under MedtrnicXPS3000 in 23 cases[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 278 -279 .
[4]

CAI Qian,SU Zhen-zhong,WEN Wei-ping,CHAI Li-ping,YE Hui,TENG Yi-shu,WU Xuan

. Relationship between adult snoring and oropharyngeal stenosis scoring[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 289 -292 .
[5] MA Jing,LIU Bin .

Effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 310 -312 .
[6] HE Xiao-song,LEI Xun,LING Yue-fu,DENG Ming .

Velopharyngeal insufficiency following radiotherapy in patients with nasopharyngeal carcinoma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 313 -315 .
[7]

ZHANG Xue-bin,GAO Yong-ping,CAI Jun-ming,LI Ming-jiang,LIN Qun,LI Chun-miao

.

Endoscopic medial maxillectomy in treatment of inverted nasal papilloma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 320 -321 .
[8] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 331 -332 .
[9] WANG Jian-rong,ZHANG Chen-ming,LIU Wei,LI Ying-mei,WEI Ning . Ultrasound biomicroscopy in angle-closure glaucoma surgery[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 359 -361 .
[10] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 369 -372 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd