Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (3): 19-25.doi: 10.6040/j.issn.1673-3770.1.2020.025

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A review of autofluorescence imaging of the parathyroid gland

SONG Xicheng1, ZHENG Haitao2   

  1. Yantai Yuhuangding Hospital Affiliated to Qingdao University, 1. Department of Otorhinolaryngology & Head and Neck Surgery;
    2. Department of Thyroid Surgery, Yantai 264000, Shandong, China
  • Online:2020-05-20 Published:2020-06-29

Abstract: The temporary and permanent dysfunction caused by parathyroid injury are inevitable. The parathyroid contains a special fluorescent substance, although its mechanism is not clear. At present, two kinds of autofluorescence detection equipment(FLUOBEAM ® imaging system, PTeye fiber probe contact system)can be used for real-time localization of the parathyroid gland for intraoperative localization and protection. The major advantage of this technique is that is allows detection of the parathyroid in excised specimens. The ratios of autofluorescence intensities of the parathyroid and thyroid are 1.23 and 7.71, respectively. The proportion of autofluorescence parathyroid identification sensitivity was 76.3-98.0% and the accuracy was 90.5-99.0%. The parathyroid gland autofluorescence technique is non-invasive, less time-consuming, provides accurate real-time information, and does not use dye as a contrast agent.

Key words: Parathyroid glands, parathyroid protection, autofluorescence, progress, review

CLC Number: 

  • R739.91
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