Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (4): 75-79.doi: 10.6040/j.issn.1673-3770.1.2020.043

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Prevalence and risk factors of central serous chorioretinopathy in a hospital-based population YANG Xiufen, YOU Ran, MA Xiumei, WANG Kang, WANG Yanling Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, ChinaAbstract:Objective〓

To describe characteristics and risk factors associated with central serous chorioretinopathy(CSC)in a hospital-based outpatient sample population. MethodsIn this hospital-based cross-sectional study, CSC patients were recruited from the Beijing Friendship Hospital from 01/2019 to 12/2019. All participants underwent a standardized interview. Logistic regression models were used to assess the risk factors associated with CSC. ResultsA total of 23,878 outpatients were recorded during the period 01/2019-12/2019. Of these, 45 patients(0.19%)were diagnosed with CSC, divided in 37 male patients(82.22%)and 8 female patients(17.78%). The patients′ age ranged from 21 to 65(42.3±10.1)years. Three patients(6.67%)presented a bilateral involvement. Of all the patients, 39 were included in the present analysis. Control patients were matched for age and sex at a ratio of 1:1. The presence of CSC was associated with exposure to steroids(OR=5.04, 95% CI:1.11-22.89), sleep time(going to sleep after 12 pm)(OR=4.16, 95% CI:1.33-13.04)),and shift-work(OR=5.74, 95% CI:1.47-22.45).ConclusionsOur data showed that CSC prevalence in the analyzed outpatients was 0.19%. Exposure to steroids, sleep time, and shift-work were factors related with CSC in the observed population.   

  1. Key words: Central serous chorioretinopathy;
    Risk factors;
    Prevalence;
    Exposure to stroids;
    Sleep time;
    Shift-workers 中心性浆液性脉络膜视网膜病变(Central Serous Chorioretinopathy, CSC)是继年龄相关性黄斑变性、糖尿病视网膜病变以及视网膜静脉阻塞等疾病之后处于第四位的常见威胁视力的视网膜病变［1-2］。该病的特征是黄斑部位局限性浆液性的视网膜神经上皮层脱离, 伴或不伴有视网膜色素上皮层脱离。CSC确切病因及发病机制尚未明确。流行病学及临床资料显示该病好发于中青年, 男性多于女性;
    其他相关的危险因素有A型人格, 心理压力, 外源性或者内源性激素水平增加、吸烟等［2-6］;
    也有报道［2, 6-7］该病发生与其他全身病相关, 例如高血压、过敏性呼吸道疾病、冠心病、消化道溃疡等与其发生有关。此外, 近几年来也有研究显示工作性质(是否为轮班工作)［8-10］以及睡眠障碍等［9, 11-12］因素与CSC的发病相关。
  • Received:2020-05-18 Online:2020-07-20 Published:2020-08-28

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Abstract: Objective To describe characteristics and risk factors associated with central serous chorioretinopathy(CSC)in a hospital-based outpatient sample population. Methods In this hospital-based cross-sectional study, CSC patients were recruited from the Beijing Friendship Hospital from 01/2019 to 12/2019. All participants underwent a standardized interview. Logistic regression models were used to assess the risk factors associated with CSC. Results A total of 23,878 outpatients were recorded during the period 01/2019-12/2019. Of these, 45 patients(0.19%)were diagnosed with CSC, divided in 37 male patients(82.22%)and 8 female patients(17.78%). The patients' age ranged from 21 to 65(42.3±10.1)years. Three patients(6.67%)presented a bilateral involvement. Of all the patients, 39 were included in the present analysis. Control patients were matched for age and sex at a ratio of 1:1. The presence of CSC was associated with exposure to steroids(OR=5.04, 95% CI:1.11-22.89), sleep time(going to sleep after 12 pm)(OR=4.16, 95% CI:1.33-13.04)),and shift-work(OR=5.74, 95% CI:1.47-22.45).Conclusions Our data showed that CSC prevalence in the analyzed outpatients was 0.19%. Exposure to steroids, sleep time, and shift-work were factors related with CSC in the observed population.

Key words: Central serous chorioretinopathy, Risk factors, Prevalence, Exposure to stroids, Sleep time, Shift-workers

CLC Number: 

  • R774.5
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