Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (5): 7-13.doi: 10.6040/j.issn.1673-3770.1.2020.078

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Effects of aging on galvanic vestibular stimulation elicited vestibular evoked myogenic potential

  

  • Received:2020-08-06 Published:2020-11-17

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Abstract: Objective To observe the effect of age on cervical vestibular-evoked myogenic potential(cVEMP)and ocular vestibular-evoked myogenic potential(oVEMP)elicited by galvanic vestibular stimulation(GVS)in healthy subjects. Methods Sixty-one healthy volunteers(122 ears)aged 22-81 years(45.0±13.8 years)were recruited as study subjects and divided into three groups according to age: 20-40(26 patients, 52 ears), 41-60(24 patients, 48 ears), and >60(11 patients, 22 ears)years. Each subject underwent both GVS-cVEMP and GVS-oVEMP. The elicit rate, threshold, p1 latency, n1 latency, amplitude, and interaural amplitude asymmetry ratio of both VEMPs were calculated and compared among the age groups. SPSS 18.0 software was used for statistical analyses. Results The elicit rates of GVS-cVEMP were 96.15%, 89.58%, and 95.45% in age groups of 20-40, 41-60, and >60 years, respectively, without any statistically significant difference among groups(P>0.05). However, the elicit rates of GVS-oVEMP were 98.07%, 91.67%, and 72.13% in age groups of 20-40, 41-60, and >60 years, respectively, showing a decreased tendency with growing age(P<0.05). In the parametric analysis, the elicit rate, threshold, p1 latency, n1 latency, amplitude, no amplitude asymmetry ratio of cVEMP were not statistically correlated with age(P>0.05). However, growing age showed decreased elicit rate, increased threshold, and decreased amplitude of oVEMP(P<0.05)but no difference in the n1 latency, p1 latency, or amplitude asymmetry ratio. Conclusion With growing age, the function of peripheral vestibular system decreased, which might affect GVS-cVEMP and GVS-oVEMP.

Key words: Vestibular evoked myogenic potential, Cervical vestibular evoked myogenic potential, Ocular vestibular evoked myogenic potential, Galvanic vestibular stimulation, Age

CLC Number: 

  • R764.3
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