JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

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Ultrastructure of the surfactant lamellar bodies in the nasal mucosa of guinea pigs

JI Xiao-bin1， LIU Xi-hong2， ZANG Lin-quan3，WANG Lei1， XIE Jun3   

  1. 1. Department of Otorhinolaryngology, Guangzhou First People′s Hospital， Guangzhou 510180;2. Department of Microscopy, Guangzhou Medical College, Guangzhou;3. Department of Pharmacology, School of Pre-clinical Medicine, Sun Yat-sen University
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-12-24 Published:2007-12-24
  • Contact: JI Xiao-bin

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Abstract: Objective To observe the ultrastructure of surfactant lamellar bodies in the nasal mucosa. Method The nasal mucosa of 8 normal guinea pigs were observed. Result Lamellar bodies were scattered in the nasal mucosa and they were circular, lamellar- and coil-like small bodies with compact electron densities. Conclusion The nasal mucosa has lamellar bodies whose secreted surfactants play a role in nasal function and pathophysiology.

Key words: Nasal mucosa, Surfactant, Lamellar bodies, Ultrastructure

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