Abstract:

Objective  To investigate the clinical features of laryngeal carcinoma in females in the East of Shandong Province. Methods  Twenty-two female patients with laryngeal carcinoma were retrospectively analyzed, including 8 cases of supraglottic carcinoma, 13 cases of glottic carcinoma and 1 case of subglottic carcinoma. According to AJCC（2002）, there were 10 cases in stageⅠ, 2 cases in stageⅡ,4 cases in stage Ⅲ, and 6 cases in stage Ⅳ. Partial laryngectomy was performed in 14 patients and total laryngectomy in 6 patients. 10 patients underwent neck dissection synchronously. Radiotherapy was performed in 10 patients after surgery. And 2 patients only received radiotherapy. The direct method was used to calculate the survival rate. Results  Among the 20 patients who received surgery, 11 were followed up for more than 3 years: 2 were missed and 8 were disease-free survival. The 3-year survival rate was 72.7%. Only 6 patients were followed up for more than 5 years: 1 was missed and 5 were disease-free survived. The 5-year survival rate was 83.3%. The two patients who only received radiotherapy died because of the relapse in 9 months and 1 year after treatment respectively. Conclusion  Laryngeal carcinoma in females has a low incidence. Supraglottic carcinoma is relatively common in female patients. Smoking is an important factor in some females. Multiple primary carcinomas should be focused on in females.

Key words: Laryngeal neoplasms; Carcinoma, Squamous cell; Female; Surgery; Survival rate