JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2011, Vol. 25 ›› Issue (3): 15-.

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Preliminary study of animal models for laryngeal surgery

XU Hong-ming， DONG Pin， SUN Zhen-feng， WANG Guo-liang， WANG Fei   

  1. Department of Otolaryngology-Head and Neck surgery, the First Hospital affiliated to Shanghai Communication University，Shanghai 200080， China
  • Received:2010-10-08 Revised:2010-12-15 Online:2011-06-16 Published:2011-06-16

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Abstract:

Objective      To study an animal model for laryngeal surgery by measuring relevant parameters during the operation and peri-operative period in canines. Methods      10 beagles underwent laryngofissure and basic parameters of the laryngeal cavity were measured during the operation. Then, 10 beagles underwent tracheotomy and nasogastric feeding and the postoperative status was observed. Results      Canines and humans showed similar parameters of the laryngeal cavity. Canines could sustain postoperative tracheotomy and nasogastric feeding. Conclusions     It is suitable to choose canines as the experimental animal. And the schemes of  the operation and peri-operative treatment are clear.

Key words: Laryngocarcinoma; Animal experiment; Tracheotomy; Nasogastric feeding

CLC Number: 

  • R739.65
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