Abstract:

Objective   To study the clinical and pathological characteristics of sinonasal neoplasms in children and elderly. Methods   A cohort of hospitalized children and old patients confirmed by surgical pathology with sinonasal tumors were enrolled in this study. The characteristics, in terms of gender, origin, disease component ratio and therapeutic methods were reviewed. Results   ① In this series of children, there were 15 males and 15 females and the ratio of benign to malignant tumors was 2.3∶1. 15 neoplasms arose from the nasal cavity and 15 tumors arose from sinus. In the series of elderly patients, there were 53 males and 29 females and the ratio of benign to malignant tumors was 1∶1.2. 49 tumors arose from the nasal cavity, while, 33 neoplasms derived from sinus. ② The disease component ratio of children decreased in order of softtissue, lymphohematopoietic tissue, bone and cartilaginous tissue, ectopic intracranial tumors, and epithelial tissue. The disease component ratio of the elderly decreased in order of epithelial tissue, softtissue, bone and cartilaginous tissue, lymphohematopoietic tissue, and ectopic intracranial tumors. ③ Surgery is the main method for these benign tumors. And comprehensive treatment, in combination with other therapeutic methods, is the main strategy for malignant tumors.  Conclusions   Tumors in children and elderly from different parts of the nasal cavity and paranasal sinus have specific clinical and pathological characteristics. Comprehensive treatment is the main therapeutic method for these tumors.

Key words:  Pediatrics; Elderly； Sinonasal neoplasms; Clinical， pathology; Therapy