JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2012, Vol. 26 ›› Issue (1): 19-21.

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Correlation between blood trace element and obstructive sleep apnea hypopnea syndrome in children

WANG Bo-tao, HOU Jin, ZHANG Xiang-hong, ZHU Kang,  LIANG Jian-min   

  1. Department of Otorhinolaryngology, Second Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an  710004, China.
  • Received:2011-11-10 Online:2012-02-16 Published:2012-02-16
  • About author:王波涛。Email:wjbotao@163.com

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Abstract:

Objective   To determine the changes of blood trace element levels in children suffering obstructive sleep apnea hypopnea syndrome (OSAHS). Methods   65 children aged 3-14 years with OSAHS were selected as the OSAHS group, and 43 children of similar age without OSAHS (excluded any other diseases that could result growth retardation or hypoxemia) were chosen as the control group. The plasma concentration of copper，zinc，iron，calcium and magnesium were measured by flame atomic absorption spectrophotometry. Results   Statistical analysis was conducted and the results were as follows: the plasma concentration of copper in the OSAHS group were higher than in the control group(P<0.01), while the zinc and calcium levels in serum of the adenoid hypertrophy group were lower than the control group(P<0.01). No significant difference was found between the iron and magnesium level(P>0.05). Conclusion   In the children with OSAHS, the plasma concentrations of copper, zinc and calcium have changed, while iron and magnesium levels do not.

Key words: Sleep apnea, obstructive; Metal element; Child

CLC Number: 

  • R766.7
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