JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2012, Vol. 26 ›› Issue (4): 78-81.

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Immunologic mechanism of cytokines in otitis media with effusion

MA Hui-qin, ZHANG Zhi-jun   

  1. Department of Otorlaryngology, Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • Received:2011-11-23 Online:2012-08-16 Published:2012-08-16

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Abstract:

There were a lot of researchs performed on the immunologic mechanism related to otitis media with effusion(OME) at home and abroad in the recent years, especially the type I allergy, cytokines related to Th1/Th2 , the interactions among these cytokines  and tumor necrosis factor-α(TNF-α), interferon-γ(IFN-γ), nuclear transcription factors kappa B (NF-kB), oxygen radicals, hypoxia inducible factor-1α(HIF-1α), transforming growth factor-β(TGF-β), or intercellular adhesion molecule (ICAM). The progress was reviewed and some new ideas is to be proposed in this paper. 

Key words: Otitis media with effusion; Cytokine; Immunologic mechanism

CLC Number: 

  • R764.21
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