J Otolaryngol Ophthalmol Shandong Univ ›› 2013, Vol. 27 ›› Issue (5): 68-70.doi: 10.6040/j.issn.1673-3770.0.2013.260

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Riboflavin/UVA-induced corneal crosslinking in the treatment of fungal corneal ulceration

CUI Chang-xia1, ZHU Wei2, ZHANG Chun-xiao3, LI Zhi-wei3   

  1. 1.Physical Examination Center, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China;  2. Department of Ophthalmology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China;  3. Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
  • Received:2013-09-10 Online:2013-10-16 Published:2013-10-16

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Abstract:

Objective      To observe the safety and efficacy of riboflavin/UVA-induced corneal crosslinking in the treatment of fungal corneal ulceration. Methods      21 fungal ulceration patients underwent corneal crosslinking, followed by local anti-fungus medication. Slit-lamp and OCT were used to observe the healing process and the inflammation signal. Results       The ulceration disappeared and inflammation signal decreased in all the patients after crosslinking treatment. Among them, 5 recovered within 1 week, 11 recovered within 2 weeks, 4 healed within 1 month and one case was noneffective. No corneal crosslinking-related complication was observed. Conclusion       Corneal crosslinking combined with local anti-fungus medication can effectively treat fungal corneal ulceration.

Key words: Crosslinking, Riboflavin, Ultraviolet A, Fungus, Corneal ulceration

CLC Number: 

  • R772.21
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[2] ZHANG Chun-xiao, LI Zhi-wei, XU Wen-wen, LI Feng-jiao, TAO Xiang-chen, MU Guo-ying. Efficacy and safety evaluation of UVA/riboflavin crosslinking for late and thin cornea keratoconus [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(2): 86-88.
[3] ZHU Fa-mei, ZHENG Jia-fa, CHEN Zu-yao, WANG Min. Analysis on therapeutic efficacy of endoscopic nasal surgery with different approaches for treating fungal maxillary sinuisitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(6): 23-25.
[4] ZHENG Jiong, LI Jing. Characteristics of computed tomography of fungal rhino-sinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(5): 45-48.
[5] SHEN Zhi-hao1, WU Su-juan1, ZHANG Wei-tian2. Maxillary sinus irrigation in treating fungal ball maxillary sinusitis under endoscopic sinus surgery [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(5): 44-46.
[6] LIU Xiang, CHEN Qiu-jian, ZOU Hua, DING Jian-hui. Brain cotton technique in endoscopic middle meatus antrostomy for removing maxillary fungus ball [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(1): 38-40.
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