JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (6): 71-73.doi: 10.6040/j.issn.1673-3770.0.2015.312

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Effect of glycosylated hemoglobin on dry eye in patients with type 2 diabetes mellitus

WANG Luping, WU Xinyi   

  1. Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2015-07-28 Online:2015-12-16 Published:2015-12-16

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Abstract: Objective To evaluate the effect of glycosylated hemoglobin on dry eye in patients with type 2 diabetes mellitus. Methods A total of 140 patients with type 2 diabetes mellitus were collected and divided into two groups: poor in glucose control group (n=70) and good in glucose control group (n=70), according to the level of glycosylated hemoglobin A1c (HbA1c). All patients were inquired about dry eye svndrome and received the examinations as follows: Schirmer I test (SIt), tear break-up time (BUT) and corneal fluorescein staining (FL). Results The elderly and male patients of poor in glucose control group showed higher incidence of dry eye syndrome than that of good in glucose control group, showing a significant difference between two groups (P<0.05). The elderly patients of poor in glucose control group showed lesser SIt and faster BUT than controls (P<0.05); there were no differences among SIt, BUT in young and middle patients of two groups. HbA1c level was positively correlated with dry eye svndrome, and negatively correlated with SIt, BUT. Conclusion The HbA1c level was correlated with dry eye in elderly patients with type 2 diabetes mellitus. It has great clinical value by controlling the glycosylated hemoglobin levels on patients with type 2 diabetes mellitus.

Key words: Dry eye, Glycosylated hemoglobin A1c, Type 2 diabetes mellitus

CLC Number: 

  • R587.2
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