JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (3): 32-36.doi: 10.6040/j.issn.1673-3770.0.2015.491

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Analysis of the risk factors of proliferative laryngopharyngeal disease.

HE Guijun1,2, QIAN Xiaoyun1, GU Yajun1, LIN Chuanyao1, SONG Panpan1, GAO Xia   

  1. 1. Department of Otolaryngology &Head and Neck Surgery, Drum Tower Clinical Medical College of Nanjing Medical University, Nanjing 210000, Jiangsu, China;2. Lianyungang Second Peoples Hospital, Lianyungang 222000, Jiangsu, China
  • Received:2015-11-18 Online:2016-06-16 Published:2016-06-16

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Abstract: Objective To investigate the risk factors of proliferative laryngopharyngeal disease(PLD). Methods A total of 471 patients with PLD were included in this retrospective study. Their general information, clinical data, reflux symptom index(RSI)and reflux fluiding score(RFS)were statistically analyzed. Results Smoking, alcohol, RSI, RFS and gastrosis were correlated with PLD(P<0.05), while age, sex and BMI were not correlated. Age, sex, smoking, alcohol and RFS score were significantly correlated with the nature of PLD(P<0.001), BMI was significantly correlated(P<0.05), while RSI score and gastrosis were not correlated. Logistic regression analysis indicated that age, gender, smoking, alcohol and RFS score were independent risk factors for the development of PLD(P<0.05). Conclusions The risk factors for PLD include smoking, alcohol, RSI, RFS and gastrosis. The benign or malignant nature of PLD is related to age, sex, smoking, alcohol, RFS and BMI.

Key words: Reverse fluid sign score, Etiology, Reflux symptom index, Pharyngolaryngeal disease

CLC Number: 

  • R739.65
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