JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (3): 68-72.doi: 10.6040/j.issn.1673-3770.0.2015.456

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Participation of cAxin2 in the development of inner ear of chick embryo.

ZHANG Xiaobing1, DAI Fangping2, HOU Yun1, Brand-Saberi B   

  1. 1. Department of Otolaryngology &Head and Neck Surgery, First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China;2. Department of Anatomy and Molecular Embryology, Institute of Anatomy, Ruhr University Bochum, 44780 Bochum, Germany
  • Received:2015-10-30 Online:2016-06-16 Published:2016-06-16

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Abstract: Objective To observe the expression of the Wnt families negative regulator cAxin2 in the development of inner ear of chick embryo. Methods The fertilized white leghorn eggs were hatched and chick embryos were butchered in HH11-28 stages according to the Hamburger and Humilton(1951)staging criteria. The embroys were fixed and hybridized in situ and sectioned. Results Chick homolog gene, cAxin2, expressed in the otic cup beginning at stage HH14+ and exhibited a dynamic expression pattern during formation and further differentiation of the otic vesicle. Conclusion cAxin2 participate in inner ear development of Chick embryo.

Key words: Chick, cAxin2, Inner ear development

CLC Number: 

  • R764
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