JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (5): 101-105.doi: 10.6040/j.issn.1673-3770.0.2016.019

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A clinical analysis of CO2 laser microsurgery for early glottic laryngeal carcinoma with anterior commissure involvement.

BAO Weijing1, NING Jiayu2, ZHU Zhongshou1, WEI Rifu1, LIN Chang   

  1. 1. Department of Otolaryngology &Head and Neck Surgery, Ningde Municipal Hospital, Ningde 352100, Fujian, China;2. Department of Pathology, Ningde Municipal Hospital, Ningde 352100, Fujian, China;3. Department of Otorhinolaryngology, First Affiliated Hospital of Fujian Medical University, Fuzhou 350004, Fujian, China
  • Received:2016-01-18 Online:2016-10-20 Published:2016-10-20

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Abstract: Objective To explore the clinical safety and curative effect of CO2 laser microsurgery in the treatment of early glottis carcinoma with anterior commissure involvement. Methods Clinical data of 26 cases of early glottic laryngeal carcinoma with anterior commissure involvement treated with CO2 laser microsurgery were retrospectively analyzed. Surgical specimens were conventionally embedded with paraffin and serially sectioned, and then stained using hematoxylin-eosin for pathologic examination. All patients were closely followed up to observe the local recurrence rate. Results Of all 26 surgical margins, 20 were negative and 6 were positive. Relapse was detected in 7 cases, the recurrence rate being 26.9%(7/26). The recurrence rate of positive and negative surgical margins was 83.3%(5/6)and 10%(2/20), respectively, with statistical differences(P=0.002). Conclusion CO2 laser microsurgery can safely and effectively preserve the vocal function of early stage glottis carcinoma with anterior commissure involvement. However, the operation indications should be strictly followed in order to guarantee safe surgical excision and reduce local recurrent rate.

Key words: Laser surgery, Anterior commissure involvement, Recurrence rate, Safe surgical margin, Glottis carcinoma

CLC Number: 

  • R739.6
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