JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2014, Vol. 28 ›› Issue (6): 18-20.doi: 10.6040/j.issn.1673-3770.0.2014.070

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Clinical trial of postaurical drug injection to treat sudden hearing loss

JIANG Chao-yong, CAI Yong-ming, YIN Ya-lei   

  1. Department of Otolaryngology, Shenzhen Bao'an District Shajing People's Hospital, Shenzhen 518104, Guangdong, China
  • Received:2014-02-26 Published:2014-12-16

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Abstract: Objective To evaluate the postaurical injection of corticosteroids to treat sudden hearing loss. Methods 65 patients with sudden hearing loss were divided into postaurical injection group (n=32) and intratympanic administration group (n=33). In addition to conventional medication, two groups were injected dexamethasone 0.5 mg through postaurical or intratympanic approaches on every three days in a 14-day course. Results The hearing improvement in postaurical injection group and intratympanic administration group were 13.2±8.6 dB and 14.6±11.1 dB. Compared to the pre-treatment, the differences were significant in both groups (P<0.05), however, no significant difference were noted between the groups (P>0.05). Adverse reactions occurred less in experimental group than the control (P<0.05). Conclusion Postaurical injection is effective, simple and safe to treat sudden hearing loss, which can serve as an alternative for intratympanic administration.

Key words: Sudden hearing loss, Postaurical injection, Intratympanic injection, Dexamethasone

CLC Number: 

  • R764.43
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