JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (2): 94-97.doi: 10.6040/j.issn.1673-3770.0.2015.372

Previous Articles     Next Articles

Clinical observation on the effects of three surgical methods for pterygium.

WANG Dan, WANG Rui, ZHANG Qiming, WANG Liwen   

  1. Department of Ophthalmology, Affiliated Hospital of Jianghan University(the Sixth Hospital of Wuhan City), Wuhan, 430015, Hubei, China
  • Received:2015-09-02 Online:2016-04-16 Published:2016-04-16

PDF (PC)

714

Abstract: Objective To compare the therapeutic effects of simple pterygium excision, pterygium excision combined with free conjunctival flap transplantation and pterygium excision combined with autologous corneal limbus stem cell transplantation in the treatment of pterygium. Methods Totally 162 patients(186 eyes)were randomly divided into Group A, B and C. Group A were treated with simple pterygium excision, Group B with pterygium excision combined with free conjunctival flap transplantation, and Group C with pterygium excision combined with autologous corneal limbus stem cell transplantation. The recurrence rate, incidence of complications and change of tear function after surgeries were compared among the three groups. Result Group A was significantly lower than Group B and C in the cure rate, was higher than Group B and C in the incidence of complications and recurrence rate, and was longer than Group B and C in repair time(P<0.05). The incidence of complications, recurrence rate were lower and cure rate and repair time were better in Group C than those in Group B(P<0.05). The early postoperative tear films stability of Group B and C were better than that of Group A, with statistically significant difference(P<0.05). Conclusion Compared with single pterygium excision and pterygium excision combined with free conjunctival flap transplantation, pterygium excision combined with autologous corneal limbus stem cell transplantation is an effective method to treat pterygium,which can reduce the rate of complications, the recurrence,and improve tear function for patients with pterygium.

Key words: Pterygium, Conjunctival flap transfusion, Tear film, Autologous corneal limbus stem cell transplantation

CLC Number: 

  • R779.6
[1] Rezvan F, Hashemi H, Emamian M H, et al. The prevalence and determinants of pterygium and pinguecula in an urban population in Shahroud, Iran[J]. Acta Med Iran, 2012, 50(10): 689-696.
[2] 李兆瑞, 刘二华. 原发性翼状胬肉发病机制和治疗新进展[J]. 国际眼科杂志, 2012, 12(4): 660-663. LI Zhaorui, LIU Erhua. Research advancement in pathogenesis and therapy of primary pterygium[J]. Inter Eye Sci, 2012, 12(4): 660-663.
[3] Gulkilik G, Kocabora S, Taskapili M, et al. A new technique for pterygium excision: air-assisted dissection. Ophthalmologica[J]. 2006, 220(5): 307-310.
[4] Katirciolu Y A, Altiparmak U E, Duman S. Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C[J]. Orbit,2007, 26(1): 5-13.
[5] 宋小平, 李育广, 危高生, 等. 两种术式治疗翼状胬肉疗效观察[J]. 实用中西医结合临床, 2012, 12(3): 51-52. SONG Xiaoping, LI Yuguang, WEI Gaosheng, et al. Observation on two kinds of surgical methods for treating pterygium[J]. Prac Clin J Integ Trad Chin West Med, 2012, 12(3): 51-52.
[6] 田瑾, 刘梅,刘孟军, 等. 自体角膜缘干细胞移植治疗翼状胬肉临床分析[J].陕西医学杂志, 2012, 41(1): 118-119. TIAN Jin, LIU Mei, LIU Mengjun, et al. Clinical analysis of autologous corneal limbus stem cell transplantation for treating pterygium[J]. Shaanxi Med J, 2012, 41(1): 118-119.
[7] 张秋玲,李建强,黄扬.自体角膜缘干细胞移植术治疗翼状胬肉疗效分析[J].吉林医学, 2013, 34(22): 4501-4502. ZHANG Qiuling, LI Jianqiang, HUANG Yang. Effect of autologous corneal limbus stem cell transplantation for treating pterygium[J]. Jilin Med J, 2013, 34(22): 4501-4502.
[8] 李绍军.角膜干细胞移植治疗翼状胬肉的疗效分析[J]. 国际眼科杂志, 2011, 11(2): 360-361. LI Shaojun. Corneal stem cell transplantation in the treatment of pterygium[J]. Inter Eye Sci, 2011, 11(2): 360-361.
[9] 邢怡桥, 但汉东, 李拓, 等. 自体角膜缘干细胞移植治疗翼状胬肉Meta分析[J]. 中国实用眼科杂志, 2013, 31(4): 433-437. XING Yiqiao, DAN Handong, LI Tuo, et al. A Meta-analysis of limbal autograft in treatment of pterygium[J]. Chin J Prac Ophthalmol, 2013, 31(4): 433-437.
[10] Esquenazi S. Autogenous lamellar scleral graft in the treatment of scleral melt after pterygium surgery[J]. Graefes Arch Clin Exp Ophthalm, 2007, 245(12):1869-1871.
[1] WENG Biyan, LIU Can. Impact of scleral tunnel incision and clear corneal incision on the tear film of patients with cataract after phacoemulsification. [J]. J Otolaryngol Ophthalmol Shandong Univ, 2017, 31(4): 80-83.
[2] DAI Lihua, GUO Xia, ZHANG Jingjing. Changes of tear film and tear secretion in patients before and after pterygial excision combined with conjunctival autografts. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 67-69.
[3] SHENG Xia, CHEN Hui, DENG Hong, XIE Qing. Analysis of efficacy of corneal bandage lens after pterygium resection. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 109-112.
[4] KONG Xiangfeng. Effect of pterygium excision with limbal-conjunctival flap grafting and wearing corneal contact lens [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(3): 93-94.
[5] LI Mei. Clinical observation of modified pterygium excision with limbal-conjunctival flap grafting [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(2): 89-90.
[6] YU Xiao-ming, WU Xin-yi. Meta-analysis of limbal stem cell transplantation and amniotic membrane transplantation for pterygium [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(1): 66-71.
[7] ZHU Wei1, MU Guo-ying2. Effect of different depth of corneal flap on dry eye syndrome after corneal refractive operation [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(5): 1-2.
[8] WANG Yuxia, XIAO Ying， SUN Hongyi, GAO Xue， LIU Jing， CHEN Guoling, YANG Lixia. Four surgical treatments of pterygium on 168 eyes [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2010, 24(3): 64-66.
[9] WANG Xu,ZHANG Hua,LV Li-ping,CUI Lei,LI Miao . Quality of tear film of adolescence during internet terminal use [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 265-268 .
[10] SI Yan-fang,GUAN Juan,ZHOU Li,SHENG Yu . Changes of tear film following cataract surgeries in highly senile patients with age-related cataracts [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(1): 13-16 .
[11] YAN Rui,ZHU Lin-jie . Transplantation of limbal autograft following microsurgery for pterygium [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(3): 243-244 .
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] WANG Xiao-ye, YOU Jian-qiang, QIU Jian-he. Quality of life in patients under care of sublingual immunotherapy[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(3): 13 -15 .
[2] ZHU Wenyan, JIN Xin, SHE Wandong, MA Yongchi. Assessment of psychopathological characteristics in 30 patients with sudden sensorineural hearing loss[J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 50 -52 .
[3] ZHOU Hui, HUANG Xue-qin, HU Jun-li, YAO Jun, ZHANG Yue-fei, JIANG Feng. Experimental study on Scutellarin influence DEX in the process of chemotherapy for nasopharyngeal carcinoma[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(4): 30 -32 .
[4] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(3): 266 -266 .
[5] SU Faren, DING Jinghua, LIU Xingang, BO Lin. Bone-anchored hearing aids softband implanted in patients with bilateral congenital microtia.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(1): 74 -75 .
[6] ZHAO Lu, XIE Guoli, WANG Yanling. Changes of ocular hemodynamics after intravitreal ranibizumab injection in patients with wet age-related macular degeneration.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 101 -104 .
[7] TAO Yu, ZHANG Shi-xi, CHAI Xue-rong, SHEN Jia-quan. Clinical study on glaucoma patients’ quality of life and related factors[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(2): 84 -86 .
[8] LIANG Song-min1, GUO Yong-wei2, ZHAO Xia1. The diagnostic effectiveness of  portable monitors device  in obstructive sleep apnea hypopnea syndrome[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(2): 22 -25 .
[9] JIANG Chao-yong, CAI Yong-ming, YIN Ya-lei. Clinical trial of postaurical drug injection to treat sudden hearing loss[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(6): 18 -20 .
[10] PANG Wen-hui1, SHI Guang-gang1, SHI Lei1, WANG He-feng2, WANG Xiao-ting1, HAN Jie1, LI Jian-feng1, WANG Hai-bo1. Experimental study on regulatory T cells and IgE, IL-4 and IL-5 in a mouse model of allergic rhinitis and in administration of nasal corticosteroid[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 29 -33 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd