Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (1): 67-70.doi: 10.6040/j.issn.1673-3770.0.2019.349

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Evaluation the efficacy of a CO2 laser and traditional exfoliation in the treatment of vocal cord leukoplakia by using objective voice analysis

SHEN Min1, QU Jining1, JIANG Yidao2   

  1. 1. Department of Otolaryngology Head and Neck Surgery, People's Hospital of Wuhan University, Wuhan 430060, Hubei, China;
    2. Department of Otorhinolaryngology, Jingzhou Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jingzhou 434020, Hubei, China
  • Published:2020-03-06

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Abstract: Objective To evaluate the efficacy of a CO2 laser and traditional exfoliation in the treatment of vocal cord leukoplakia by using objective voice analysis and to explore the value of objective voice analysis and the effects of the two treatment methods. Methods Medical records of patients with leukoplakia diagnosed in our department from January to February 2018 in 2017 were screened for CO2 and traditional exfoliation and retrospectively analyzed. The CO2 treatment group and the traditional exfoliation treatment group were denoted to be the observation and control groups, respectively; the postoperative effective rate was compared between these two groups. The Voice Disorder Index(VHI)was analyzed at 2 weeks, 1 month, and 3 months after surgery. XION DiVAS audio analysis software was used to detect preoperative and surgery 2 Weekly, January, March fundamental frequency perturbation(Jitter), amplitude perturbation(Shimmer), lowest sound intensity(SPLmin),(highest fundamental frequency)F0max, fundamental frequency(F0), longest sound duration(MPT), Voice Disorder Index(DSI). Results Compared to the control group, the observation group had a higher effective rate and a better curative effect. The VHI index in the two groups was lower than that of the preoperative group in the first and third months after operation, and the observation group The VHI index was lower than that of the control group, and the difference was statistically significant. In both groups, postoperative fundamental frequency perturbation, amplitude perturbation, and lowest sound intensity were lower than those before treatment, while fundamental frequency, longest sound duration, and snoring index was higher than those before treatment; a significant difference was noted between the observation group and the control group. The highest fundamental frequency after treatment was not significantly different from that before treatment. Conclusion For objective voice analysis, use of a CO2 laser for treatment of vocal cord leukoplakia is more effective than the use of traditional exfoliation and can significantly improve the patient's voice.

Key words: CO2 laser, Traditional stripping, Vocal cord leukoplakia, Objective voice analysis

CLC Number: 

  • R767.4
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