Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (1): 55-59.doi: 10.6040/j.issn.1673-3770.0.2021.409

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A case of an infant with embryonal rhabdomyosarcoma in the middle ear and literature review

LI Ling1,2, LI Cong1,2, SUN Yan2, CHEN Liang2   

  1. 1. The second Medical College of BinZhou Medical University, Yantai 264003, Shandong, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, Yantai Yuhuangding Hospital Affiliated to Qingdao University/ Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai 264000, Shandong, China
  • Published:2022-02-22

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Abstract: Objective Raising awareness of otolaryngologists on embryonal rhabdomyosarcoma disease. Methods The clinical data of an infant with embryonal rhabdomyosarcoma in the middle ear were analyzed, and related literatures were reviewed. Results The patient was a 10-month-old female with a bleeding mass in the left external auditory canal. Computed tomography and magnetic resonance imaging revealed soft tissue density shadows in the left external auditory meatus, tympanum, and mastoid sinus that were accompanied with an enlarged lymph node in the parapharyngeal, neck and bilateral axilla. Moreover, the diagnosis of RMS was confirmed by postoperative pathological and immunohistochemical examination after biopsy. The patient died of brain metastasis four months after the end of radiation and chemotherapy. Conclusion RMS in the middle ear is rare. Due to its obscure location and lack of typical clinical manifestations in the early stage, RMS is difficult to detect and prone to misdiagnosis. The malignant degree of this disease is high. Thus, the early detection, diagnosis, and treatment of this disease should be further studied to improve the survival rate of patients.

Key words: Middle ear, Embryonic, Rhabdomyosarcoma, Infant, Malignancy

CLC Number: 

  • R764.2
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