Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (6): 96-100.doi: 10.6040/j.issn.1673-3770.0.2021.582

• 论著 • Previous Articles    

A case report of rhino-orbitocerebral mucormycosis

SONG Huarong1, TANG Guanghua2, ZHU Renliang3   

  1. 1. The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, Guangdong, China;
    2. Department of Emergency, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong, China;
    3. Department of Otorhinolaryngology & Head and Neck Surgery, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, Guangdong, China
  • Published:2022-12-07

Abstract: Objective This study aimed summarize the diagnosis and treatment experience in the case of rhino-orbitocerebral mucormycosis(ROCM)and improve the understanding of the disease. Methods The clinical case data of a patient with ROCM were retrospectively reviewed and summarized in combination with relevant literature. Results This patient's first manifestation was oral dental soreness, with poor glycemic control previous diabetes. The relevant examinations were improved, and the diagnosis of ROCM due to Rhizopus infection was confirmed by the laboratory. After controlling the underlying disease, antifungal and surgical operations, the patient final clinical outcome was death. Conclusion ROCM mostly is seen in patients with uncontrolled diabetes. Its clinical presentation is diverse, and typically involves localized cutaneous or mucosal eschar necrosis. There was no specific manifestation in the imaging examination. Pathology and fungal culture were the gold standard for diagnosis. Early diagnosis and effective treatment, such as antifungal therapy, basic disease treatment, and surgical treatment are the key to diagnosis and treatment.

Key words: Mucormycosis, Rhino-orbitocerebral mucormycosis, Rhizopus, Diabetes, Toothache

CLC Number: 

  • R762
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