Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (2): 18-24.doi: 10.6040/j.issn.1673-3770.0.2023.291

• Original Article • Previous Articles     Next Articles

Analysis of anxiety and depression states in the treatment of chronic subjective tinnitus with masking sound therapy

DONG Xuelin, ZHANG Zhijun   

  1. Department of Otorhinolaryngology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China
  • Published:2025-03-26

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Abstract: Objective To explore the improvement of anxiety and depression status in patients with chronic subjective tinnitus after masked sound therapy and its influencing factors. Methods 256 patients with chronic subjective tinnitus were divided into observation group and control group according to the duration of masked sound therapy. The Tinnitus handicap inventory(THI), Hamilton depression scale(HAMD), and Hamilton anxiety scale(HAMA)scores of the two groups were collected before and after treatment. The changes of tinnitus degree, anxiety and depression status before and after treatment were compared, and the factors affecting anxiety and depression status were analysed. Results The efficacy rates of THI, HAMA, and HAMD scores in the observation group were significantly higher than those in the control group(P<0.001, P<0.001, P<0.001). In the observation group, multivariate binary logistic regression analysis showed that tinnitus loudness(OR=31.57, P=0.003)and pre-treatment THI level(OR=0.11, P=0.002)were independent factors for effective improvement of HAMA score, while residual inhibition result(OR=0.12, P=0.003)and pre-treatment THI level(OR=0.20, P=0.016)were independent factors for effective improvement of HAMD score. Conclusion This study found that masked sound therapy can reduce the severity of tinnitus and improve anxiety and depression. Pre-treatment THI level, tinnitus loudness, and residual inhibition results have significant effects on the effective improvement of anxiety and depression in patients with chronic subjective tinnitus.

Key words: Chronic subjective tinnitus, Masking sound therapy, Anxiety, Depression

CLC Number: 

  • R764.45
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